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MetabolomicsOral administration of low-molecular-weight heparin ameliorates colitis by enhancing the gut mucus barrier via microbial tryptophan metabolites

Background and Purpose: Previous studies have reported that oral low molecular weight heparin (LMWH) ameliorated colitis by undefined mechanisms in ulcerative colitis (UC) patients. Our study explored the mechanisms of LMWH on colitis from the perspective of gut microbiota and its metabolites.

2025-10-12 | MTBLS5770 | MetaboLights
ProteomicsQuantitative proteome in tomato
In this study, we applied a quantitative proteomic approach to identify the proteins that differentially accumulate in the mutant of an E3 ubiquitin ligase gene. Proteins were isolated from fruits of wild-type and mutant tomato plants. A total of 288 proteins were finally screened as significantly a...
ORGANISM(S): Solanum lycopersicum 
2020-11-24 | PXD018731 | Pride
Fruit Tomato Itraq 
ProteomicsUbiquitinated peptide identification in tomato
In this study, we identified ubiquitinated peptides that changed abundance in the mutant of an E3 ubiquitin ligase gene by coupling a K-(GG) peptide immunoprecipitation with quantitative proteomic analysis. Two independent replicates identified 265 and 236 ubiquitinated peptides, respectively. Seven...
ORGANISM(S): Solanum lycopersicum 
2020-11-24 | PXD018707 | Pride
Swath Fruit Ubiquitinated peptides Tomato 
ProteomicsDAXX governs the silencing of LINE1 during spermatogenesis in mice
Total protein extraction from WT mice testes was immunoprecipitated using DAXX antibody.
ORGANISM(S): Mus Musculus 
2026-01-08 | PXD072798 |
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