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Bee venom (BV) and its main compound melittin (MLT) have antioxidant, anti-inflammatory, and anti-aging activities; however, very little research has been conducted on their effects on skin aging. In this study, a mouse skin aging model induced by D-galactose (D-gal) was constructed via subcutaneous...
2025-05-12 | MTBLS11975 | MetaboLights
We identified a number of deregulated genes through transcriptome analysis on esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues. Our pathway enrichment analysis suggested that deregulated genes were strongly enriched in multiple functionally linked pathways known to be important ...
ORGANISM(S): Homo sapiens 
PS is one of the most difficult plastics to degrade, and its microplastic residues have been detected in various environments.
ORGANISM(S): Cupriavidus Sp. D4 
2025-12-28 | PXD072476 |
Bioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
ORGANISM(S): Mus Musculus 
Background Amyotrophic lateral sclerosis (ALS) is an age-dependent and incurable neurodegenerative disease. It is pathologically characterized by selective degeneration of motor neurons resulting in a catastrophic loss of motor function. Previous studies showed that excess copper (Cu) might have a r...
ORGANISM(S): Mus Musculus 
2023-01-29 | PXD039728 |
The HEK293T cells transiently expressing Flag-tagged empty vector or Flag-NRDE2-WT were lysed in NETN buffer (10 mM Tris-HCl [pH 8.0], 100 mM NaCl, 1 mM EDTA, and 0.5% NP-40) and immunoprecipitated with anti-Flag M2 agarose (M8823; Sigma-Aldrich, MO, USA). After washing four times with the high stri...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD051117 |
The T2D-GENES/GoT2D 13K exome sequencing study includes ~13,000 samples, half T2D cases and half T2D controls, from five ancestries (~5K Europeans, ~2K each of African-American, East-Asian, South-Asian, and Hispanic). Samples underwent deep exome sequencing, with SNVs and INDEls called according to ...
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