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MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3003 | MetaboLights
MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3056 | MetaboLights
ProteomicsThe mode of action of antifouling compound albofungin in inhibiting barnacle settlement
In the present study, proteomic analyses were used to investigate changes in the transcriptome and proteome of a major fouling barnacle Amphibalanus amphitrite cyprids in response to albofungin treatment.
ORGANISM(S): Amphibalanus amphitrite (Striped barnacle) (Balanus amphitrite) 
2023-02-21 | PXD039255 | Pride
Antifouling Mode of action Amphibalanus amphitrite Albofungin Transcriptomics 
ProteomicsLD4172 100nM and LD4172NC 100nM treated MDA_MB_231 cell line global proteomics
1 million MDAMB231 cells were seeded in 6-well plates. On the following day, MBAMB231 cells were treated in triplicates with DMSO, LD4172 (100 nM) or LD4172-NC (100 nM) for 6 hours. Cells were washed with ice-cold PBS three times. The cell pellets were lysed, reduced, alkylated, and digested by Easy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-07 | MSV000092377 | MassIVE
ProteomicsLD4172 and LD4172NC treated MDA_MB_231 cell line global proteomics
1 million MDAMB231 cells were seeded in 6-well plates. On the following day, MBAMB231 cells were treated in triplicates with DMSO, LD4172 (100 nM) or LD4172-NC (100 nM) for 6 hours. Cells were washed with ice-cold PBS three times. The cell pellets were lysed, reduced, alkylated, and digested by Easy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-05 | MSV000092348 | MassIVE
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