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TranscriptomicsThe gene encoding the hematopoietic stem cell regulator CCN3 (NOV) is under direct cytokine control through the transcription factors STAT5a/b.
Cytokines control the biology of hematopoietic stem and progenitor cells in part through the transcription factors STAT5a/b. CCN3/NOV has been reported as a positive regulator of hematopoietic stem and progenitor cells. We report microarray analyses of Lineage- Sca-1+ c-Kit+ (KSL) cells in the pre...
ORGANISM(S): Mus musculus 
2010-08-25 | E-GEOD-20684 | biostudies-arrayexpress
TranscriptomicsRepresentational Oligonucleotide Microarray Analysis (ROMA) array for Copy Number Variation Detection.
The identification of genetic and epigenetic alterations from primary tumor cells has become a common method to identify genes critical to the development and progression of cancer. We provide a bioinformatic analysis of copy number variation and DNA methylation covering the genetic landscape of ova...
ORGANISM(S): Homo sapiens 
2011-10-16 | E-GEOD-28013 | biostudies-arrayexpress
UnknownProgesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer.
Not available
S-EPMC7803566 | biostudies-literature
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
UnknownY-Box Binding Protein-1 Promotes Epithelial-Mesenchymal Transition in Sorafenib-Resistant Hepatocellular Carcinoma Cells.
Not available
S-EPMC7795419 | biostudies-literature
TranscriptomicsFetal liver development
Hepatoblasts emerging at E8.5 from the foregut endoderm proliferate vigorously and differentiate to hepatocytes and biliary epithelial cells. To find genes important for hepatocyte differentiation during development, we compared gene expression profiles of hepatoblasts/immature hepatocytes at E12.5 ...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-13363 | biostudies-arrayexpress
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
UnknownDynamic evolution trend and driving mechanisms of water conservation in the Yellow River Basin, China.
Not available
S-EPMC11530661 | biostudies-literature
TranscriptomicsComparative profiling in 13 muscle disease groups
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flig...
ORGANISM(S): Homo sapiens 
2005-10-14 | E-GEOD-3307 | biostudies-arrayexpress
UnknownPhoto-Induced Synthesis of Ytterbium and Manganese-Doped CsPbCl<sub>3</sub> Nanocrystals for Visible to Near-Infrared Photoluminescence with Negative Thermal Quenching.
Not available
S-EPMC11775517 | biostudies-literature
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