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UnknownRenal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-κB signaling pathway.
Not available
S-EPMC4275059 | biostudies-literature
TranscriptomicsDirect reprogramming of human fibroblasts to functional hepatocyte-like cells
Plasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (FOXA3, HNF1A and HNF4A), human fetal fibroblasts can be converted to hepatocyte-like cells (hiHep cells), expressing hepatic mar...
ORGANISM(S): Homo sapiens 
2014-03-06 | E-GEOD-42643 | biostudies-arrayexpress
TranscriptomicsIdentifying vitamin C and RA-regulated genes in the J1 mESCs
It has been demonstrated that vitamin C enhances reprogramming efficiency during inducing pluripotent stem cells, however, the underlying mechanisms are not fully understood. To find the downstream target genes of vitamin C and investigate the mechanism of vitamin C on reprogramming promotion, we pe...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-43405 | biostudies-arrayexpress
UnknownTowards precision medicine based on a continuous deep learning optimization and ensemble approach.
Not available
S-EPMC9898519 | biostudies-literature
ProteomicsG3BP orthologs interactional network
G3BP orthologs interactional network in humans and species.
ORGANISM(S): Homo Sapiens Drosophila Melanogaster Caenorhabditis Elegans 
2024-08-08 | PXD054692 |
ProteomicsDIA-based quantitative proteomics reveals the protein regulatory networks of floral thermogenesis in Nelumbo nucifera
The flower chambers of sacred lotus (Nelumbo nucifera) can maintain a relatively stable temperature during anthesis despite the large environmental temperature fluctuations. However, the regulatory mechanism of floral thermogenesis remains largely unclear. To further understand the molecular basis o...
ORGANISM(S): Nelumbo Nucifera 
2021-02-20 | PXD024269 |
ProteomicsBacterial Protoplast-Derived Nanovesicles Carrying CRISPR Cas9 Tools Efficiently Re-educate Tumor-Associated Macrophages for Cancer Immunotherapy
we developed an in vivo CRISPR-Cas9 genome editing system that targets tumor-associated macrophages (TAMs) via bacterial protoplast-derived nanovesicles (NVs) decorated with a pH-responsive PEG conjugated polymer and galactosamine-conjugated ligand
ORGANISM(S): Escherichia Coli Bl21(de3) 
2023-09-20 | PXD045507 |
ProteomicsTMT-based Quantitative analysis of Isatis indigotica leaf tissue
By conducting TMT labeled quantitative proteomic analysis on the leaves of Radix Isatidis under different stress conditions, the potential biological mechanisms of the impact of abiotic stress on the quality of Radix Isatidis were studied.
ORGANISM(S): Isatis Tinctoria 
2024-11-25 | PXD058215 |
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