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UnknownDecreased histone H2B monoubiquitination in malignant gastric carcinoma.

Aim

To investigate H2B monoubiquitination (uH2B) and H3K4 di- and tri-methylation (H3K4-2me, H3K4-3me) levels and their clinical significance in gastric cancer (GC).

Methods

Immunohistochemistry (IGC) was used to detect the differential levels of uH2B, H3K4-2me and H3K4-3me modificati...
S-EPMC3848160 | biostudies-literature
ProteomicsPPP6R3 immunoprecipitation mass spectrometry (IP-MS) data
PPP6R3 IP-MS data using KIT+ spermatogonia purified from testes of P9 wild-type mice
ORGANISM(S): Mus Musculus 
PXD056272 |
ProteomicsEIF5A couples translational control with transcriptional reprogramming through chromocenter reorganization during spermiogenesis
Translation initiation factor eIF5A facilitates protein synthesis and impacts diverse biological processes, yet its role in transcriptional regulation is poorly understood. Here we find eIF5A highly expressed in diverse spermatogenic cell types. Conditional knockout of Eif5a (SKO) causes complete in...
ORGANISM(S): Mus Musculus 
PXD067244 |
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