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TranscriptomicsThe X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agilent array data]
Embryogenesis requires the timely and coordinated activation of developmental regulators. It has been suggested that the recently discovered class of histone demethylases (UTX and JMJD3) that specifically target the repressive H3K27me3 modification play an important role in the activation of M-bM-^...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-39473 | biostudies-arrayexpress
TranscriptomicsThe X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner
This SuperSeries is composed of the following subset Series: GSE39472: X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner [ChIP-Seq data] GSE39473: The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agil...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-39222 | biostudies-arrayexpress
TranscriptomicsAn EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.
Regulation of cell-cell junction formation and regulation of cell migration were enriched among EMT (Epithelial-Mesenchymal Transition)-associated alternatively splicing events. Our analysis suggested that most EMT-associated alternative splicing events are regulated by one or more members of the RB...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30290 | biostudies-arrayexpress
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
TranscriptomicsTranscriptome analysis of CAX1/CAX3 double mutants
As part of a larger study on Cell-specific vacuolar calcium compartmentation regulates apoplastic calcium concentration, gas exchange and plant productivity we compared the transcriptome of 40day old CAX1/CAX3 double mutants to Col-0 wildtype plants. comparative: mutant versus wild-type
ORGANISM(S): Arabidopsis thaliana 
2010-10-20 | E-GEOD-23820 | biostudies-arrayexpress
UnknownEffect of a qigong intervention program on telomerase activity and psychological stress in abused Chinese women: a randomized, wait-list controlled trial.
Not available
S-EPMC4138386 | biostudies-literature
UnknownTranscriptomic Modulation Reveals the Specific Cellular Response in Chinese Sea Bass (Lateolabrax maculatus) Gills under Salinity Change and Alkalinity Stress.
Not available
S-EPMC10056482 | biostudies-literature
TranscriptomicsMLL regulated genes in LSK/CD48- hematopoietic stem cells
The histone methyltransferase mixed lineage leukemia (MLL) is essential to maintain hematopoietic stem cells and is a leukemia protooncogene. Although Hox genes are well-characterized targets of MLL and MLL fusion oncoproteins, the range of Mll-regulated genes in normal hematopoietic cells remains u...
ORGANISM(S): Mus musculus 
2013-05-24 | E-GEOD-47205 | biostudies-arrayexpress
MetabolomicsSerine Metabolism Tunes Immune Responses To Promote Oreochromis niloticus Survival upon Edwardsiella tarda Infection
Overactive immune response is a critical factor triggering host death upon bacterial infection. However, the mechanism behind the regulation of excessive immune responses is still largely unknown, and the corresponding control and preventive measures are also to be explored. In this study, we find t...
2021-08-18 | MTBLS2974 | MetaboLights
GenomicsCombined deficiency of Tet1 and Tet2 is compatible with development but leads to epigenetic instability
Tet enzymes (Tet1/2/3) convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Tet1 and Tet2 mediate 5hmC generation in mouse embryonic stem cells (ESCs) and various embryonic and adult tissues. To investigate the effects of combined deficiency of Tet1 and Tet2 on pluripotency and developm...
ORGANISM(S): Mus musculus 
2013-02-01 | E-GEOD-42396 | biostudies-arrayexpress
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