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MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
UnknownAn East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population.
Not available
S-EPMC5533021 | biostudies-literature
UnknownAn hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection.
Not available
S-EPMC6092684 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownA Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in <i>Plasmodium vivax</i> Hypnozoites.
Not available
S-EPMC9915689 | biostudies-literature
UnknownA drug repurposing approach reveals targetable epigenetic pathways in <i>Plasmodium vivax</i> hypnozoites.
Not available
S-EPMC12483515 | biostudies-literature
UnknownEating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management.
Not available
S-EPMC10332604 | biostudies-literature
UnknownComponents of Adolescent Behavioural Interventions With Eating Disorder Outcomes: Systematic Review With Intervention Mapping.
Not available
S-EPMC12690354 | biostudies-literature
UnknownCritically ill children during the 2009-2010 influenza pandemic in the United States.
Not available
S-EPMC3387899 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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