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UnknownTargeting the Ischemic Core: A Therapeutic Microdialytic Approach to Prevent Neuronal Death and Restore Functional Behaviors
Not available
S-EPMC12027531 | biostudies-literature
UnknownMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors.
Not available
S-EPMC5732754 | biostudies-literature
UnknownSequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.
Not available
S-EPMC1932545 | biostudies-literature
UnknownThe Ferric Citrate Uptake System Encoded in a Novel bla CTX-M-3- and bla TEM-1-Harboring Conjugative Plasmid Contributes to the Virulence of Escherichia coli.
Not available
S-EPMC8187952 | biostudies-literature
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
UnknownA Phase II Study of Sequential Capecitabine Plus Oxaliplatin Followed by Docetaxel Plus Capecitabine in Patients With Unresectable Gastric Adenocarcinoma: The TCOG 3211 Clinical Trial.
Not available
S-EPMC4998286 | biostudies-literature
ProteomicsIdentification of stably expressed reference genes for expression studies in Arabidopsis thaliana using mass spectrometry-based label-free quantification
Arabidopsis thaliana has been used regularly as a model plant in gene expression studies on transcriptional reprogramming upon pathogen infection, such as that by Pseudomonas syringae pv. tomato DC3000 (Pst DC3000), or when subjected to stress hormone treatments including jasmonic acid (JA), salicyl...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-09-05 | PXD035677 | Pride
Pathogen infection  jasmonic acid (ja)  salicylic acid (sa)  abscisic acid (aba)  expression study  label-free quantification (lfq)  rt-qpcr  reference gene 
UnknownTaming m-Quionodimethanes by Dispersion Force: Cyclodimerization of (Trialkylsilyl)Ethynyl-Substituted Indeno[2,1-b]Fluorenes and Fluoreno[2,3-b]Fluorenes.
Not available
S-EPMC12462229 | biostudies-literature
UnknownTargeting cancer stemness mediated by BMI1 and MCL1 for non-small cell lung cancer treatment.
Not available
S-EPMC9401641 | biostudies-literature
ProteomicsPyruvate kinase M2 modification by a lipid peroxidation byproduct acrolein contributes to kidney fibrosis
This study used a proteomic approach with an anti-Acr-PC antibody followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis to identify several acrolein-modified protein targets. Among these protein targets, pyruvate kinase M2 (PKM2) was found to be modified by acrolein at Cys35...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD040335 | Pride
Renal fibrosis  acrolein  pyruvate kinase m2  hypoxia-inducible factor 1-alpha  hydralazine  carnosine. 
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