Sort   by:  
 Page size 
GenomicsTranscription factor Achaete-Scute homologue 2 initiates T follicular helper cell development [ChIP-Seq]
In immune responses, activated T cells migrate to B cell follicles and develop to T follicular helper (Tfh) cells, a new subset of CD4+ T cells specialized in providing help to B lymphocytes in the induction of germinal centers 1-3. Although Bcl6 has been shown to be essential in Tfh cell function, ...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52839 | biostudies-arrayexpress
TranscriptomicsTDP-43 regulates cancer-associated microRNAs
MicroRNAs (miRNAs) play important roles in a wide range of cellular processes. Aberrant regulation of miRNA genes contributes to human diseases, including cancer. The TAR DNA binding protein 43 (TDP-43), a DNA/RNA binding protein associated with neurodegeneration, is involved in miRNA biogenesis. He...
ORGANISM(S): Homo sapiens 
2016-08-02 | E-GEOD-85065 | biostudies-arrayexpress
TranscriptomicsSpecific sequence determinants of miR-15/107 microRNA gene group targets
Using anti-Argonaute (anti-AGO) antibody co-immunoprecipitation, followed by microarray analyses and downstream bioinformatics, ‘RIP-Chip’ experiments enable direct analyses of miRNA targets. The analyses support four major findings: (i) RIP-Chip studies correlated with total input mRNA profiling pr...
ORGANISM(S): Homo sapiens 
2012-12-11 | E-GEOD-42823 | biostudies-arrayexpress
Sort   by:  
 Page size