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TranscriptomicsSeparation of DNA replication from the assembly of break-competent meiotic chromosomes
The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up to recombination, including the prolonged pre-m...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-14 | E-GEOD-35667 | biostudies-arrayexpress
GenomicsChIP-seq analysis of the cAMP binding protein (CRP) in Enteroaggregative Escherichia coli 042
ChIP-seq experiments were carried out in Enteroaggregative Escherichia coli 042. Wildtype 042 cells were grown to mid-log phase in LB medium, before being crosslinked with 1% formaldehyde and sonicated to lyse cells and shear DNA. Immunocomplexes were established using anti-FLAG antibodies. The immu...
ORGANISM(S): Escherichia coli 
2025-07-09 | E-MTAB-14748 | biostudies-arrayexpress
TranscriptomicsChromatin IP for Mcm2-7, Rec8, Hop1 and Red1
Mcm2-7 ChIP in pre-meiotic and pre-mitotic cells, axis factor ChIP in wild-type and replication compromised strains in meiosis Multiple studies of meiotic chromosomes were undertaken. To study DNA replication, the locations of replicative helicase (Mcm2-7) were mapped in pre-meiotic and pre-mitotic ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-18 | E-GEOD-35658 | biostudies-arrayexpress
GenomicsChIP-seq for LSM4 in U2OS-DIvA cells -/+ AsiSI-induction by 4OHT
Map LSM4 binding to chromatin at DNA double-strand breaks (DSBs) induced by AsiSI endonuclease in U2OS-DIvA cells.
ORGANISM(S): Homo sapiens 
2026-04-30 | E-MTAB-16861 | biostudies-arrayexpress
TranscriptomicsRatios for unsync cells
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-6664 | biostudies-arrayexpress
TranscriptomicsRatios for G1 arrested cells (Printed array)
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-6665 | biostudies-arrayexpress
TranscriptomicsPolII occupancy
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-GEOD-6667 | biostudies-arrayexpress
TranscriptomicsChIP-chip of E. coli K-12 MG1655 with antibody against PurR-8myc under various conditions.
We integrated transcription factor binding regions and mRNA transcript abundance to elucidate the PurR regulon experimentally. To measure transcription factor binding at a genome scale, we employed a ChIP-chip method to derivative strains of E. coli K-12 MG1655 harboring PurR-8myc under various con...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-06-14 | E-GEOD-26589 | biostudies-arrayexpress
TranscriptomicsFOXM1 Cistrome Predicts Breast Cancer Metastatic Outcome Better Than FOXM1 Expression Levels or Tumor Proliferation Index [RNA-Seq]
FOXM1 is a key transcription factor regulating cell cycle progression, DNA damage response, and a host of other hallmark cancer features, but the role of the FOXM1 cistrome in driving estrogen receptor-positive (ER+) vs. ER- breast cancer clinical outcomes remains undefined. Chromatin immunoprecipit...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73370 | biostudies-arrayexpress
TranscriptomicsPRMT1 interacts with leukemia fusion protein AML1-ETO for activation of transcription and transformation
Fusion protein AML1-ETO resulted from t(8;21) translocation is highly related to leukemia development. We have previously shown that the expression of AE9a, a spliced form of AML1-ETO, can rapidly cause leukemia in mouse. To understand how AML1-ETO is involved in leukemia development, we used AE9a l...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-28135 | biostudies-arrayexpress
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