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GenomicsNR2C/F orphan receptors induce telomere-genome rearrangements in ALT
Most sarcomas have complex karyotype and are characterized by multiple chromosomal rearrangements. Moreover, sarcomas very frequently maintain their telomeres by recombination in the process called Alternative Lengthening of Telomeres (ALT) which enables their continuous growth and immortalization. ...
ORGANISM(S): Homo sapiens 
2015-02-23 | E-GEOD-46237 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of soft tissue sarcoma: Expression data from Complex genetics sarcomas (cohort 1 and 2)
For this study, we selected, from the French Sarcoma Group (FSG) database, soft tissue sarcomas with no recurrent chromosomal translocations and for which a frozen tissue of the untreated primary tumor was available. Three hundred and ten sarcomas have been studied. They are split in two cohorts. W...
ORGANISM(S): Homo sapiens 
2010-06-30 | E-GEOD-21050 | biostudies-arrayexpress
TranscriptomicsExpression data from 58 Synovial Sarcomas
Background: Synovial sarcoma (SS) occur in children as well as in adults, although metastatic events are much more common in the latter. Whereas the importance of the t(X;18) translocation in SS oncogenesis is well established, the genetic basis of SS metastasis is still poorly understood. We recent...
ORGANISM(S): Homo sapiens 
2014-08-09 | E-GEOD-40021 | biostudies-arrayexpress
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