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MetabolomicsElucidation of the epitranscriptomic RNA modification landscape of chikungunya virus

The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral RNA modification in infected human cells. ...

2024-06-11 | MTBLS8697 | MetaboLights
MetabolomicsVirus-induced codon-specific reprogramming to favor viral RNA translation
Recent evidence indicates that codon usage bias regulates gene expression. How viruses, such as the emerging mosquito-borne Chikungunya virus (CHIKV), express their genomes at high levels despite an enrichment in rare codons remains a puzzling question. Using ribosome footprinting, here we analysed ...
2025-06-16 | MTBLS2443 | MetaboLights
GenomicsChikungunya virus
Chikungunya virus Genome sequencing
PRJNA473275 | ENA
GenomicsChikungunya virus
Chikungunya virus genomes from Bolivia
PRJNA609363 | ENA
GenomicsChikungunya virus
Chikungunya virus Raw sequence reads
PRJNA1511517 | ENA
GenomicsChikungunya virus
Genome sequencing of Chikungunya virus from the Americas
PRJNA294670 | ENA
GenomicsChikungunya virus
Comparative Performance of Second-Generation mNGS and Third-Generation ONT in the Molecular Epidemiology of Chikungunya Virus (PRJCA046951)
PRJDB39444 | ENA
ProteomicsAltered brain pathways following Chikungunya virus infection
A kinetic analysis of host proteome modifications in the brain of CHIKV-infected mice sampled before and after the onset of clinical symptoms was performed. The combination of 2D-DIGE and iTRAQ proteomic approaches, followed by mass spectrometry protein identification, revealed 177 significantly dif...
ORGANISM(S): Mus musculus (Mouse) 
2015-07-07 | PXD000736 | Pride
Brain Pathways modified Mouse Alphavirus Chikungunya virus Infection Itraq Pathogenesis 2d-dige 
GenomicsChikungunya virus
A field diagnosis and genotyping of chikungunya virus by a dried RT-LAMP and MinION sequencing
PRJDB7465 | ENA
ProteomicsAedes aegypti Aag-2 cells proteome modulation in response to Chikungunya virus infection
Chikungunya virus (CHIKV) is a single-stranded positive RNA virus that belongs to the genus Alphavirus and is transmitted to humans by infected Aedes aegypti and Aedes albopictus bites. In humans, CHIKV can cause painful symptoms during acute and chronic stages of infection. However, the virus-vecto...
ORGANISM(S): Aedes aegypti Chikungunya virus strain S27-African prototype Insecta 
2022-06-02 | PXD033231 | Pride
Mosquito Rna helicases. Mass spectrometry Chikungunya virus Mitochondria Label-free quantification Apoptosis Protein synthesis 
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