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TranscriptomicsCharacterization of early stages of human B cell development by gene expression profiling
We have characterized several stages of normal human B cell development in adult bone marrow by gene expression profiling of hemopoietic stem cells, early B (E-B), pro-B, pre-B, and immature B cells, using RNA amplification and Lymphochip cDNA microarrays (n = 6). Hierarchical clustering of 758 diff...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-14714 | biostudies-arrayexpress
TranscriptomicsAutoantigen promotes progression to aggressive TCL1 leukemia
Activated BCR signaling in Murine CLL leukemia cells responsive to autoantigen phosphatidylcholine Murine CLL cells obtained from spleen and peritoneum were compared for the genetic signatures associated with autoantigen responsiveness
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-45481 | biostudies-arrayexpress
UnknownAID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression.
Not available
S-EPMC8141630 | biostudies-literature
UnknownLack of intraclonal diversification in Ig heavy and light chain V region genes expressed by CD5+IgM+ chronic lymphocytic leukemia B cells: a multiple time point analysis.
Not available
S-EPMC4625536 | biostudies-literature
UnknownAID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes.
Not available
S-EPMC7204545 | biostudies-literature
TranscriptomicsIdentification of the molecular targets of microRNA-181d in murine thymocytes.
T cell-specific transgenic expression of microRNA-181d reduced number of immature CD4+CD8+ thymocytes. Microarray analysis was performed to reveal differentially expressed genes between the wild type and microRNA-181d transgenic thymocytes. Whole thymus tissues were isolated from the wild type (C57B...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-51778 | biostudies-arrayexpress
TranscriptomicsGene expression comparison of microRNA-181d Transgenic and microRNA-181d Knock-in thymocytes
T cell-specific over-expression of microRNA-181d reduced number of immature CD4+CD8+ thymocytes. Whole thymus tissues were isolated from the miR-181d transgenic (Tg-8) and miR-181d knockin (KI) mice, followed by total RNA isolation.
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-50113 | biostudies-arrayexpress
UnknownEnhanced expression of mRNA for nuclear factor kappaB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis.
Not available
S-EPMC1526601 | biostudies-literature
UnknownNovel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution.
Not available
S-EPMC5603803 | biostudies-literature
UnknownDiversification of the Ig variable region gene repertoire of synovial B lymphocytes by nucleotide insertion and deletion.
Not available
S-EPMC1430824 | biostudies-literature
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