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TranscriptomicsStau2 RIP-Chip in Mouse E13-14 Cortex
The double-stranded RNA binding protein Staufen2 (Stau2) is asymmetrically localized and segregated during asymmetric cell divisions in the developing mouse cortex and promotes intermediate progenitor cell fate. We carry out RNA immunoprecipitation with a Stau2 specific antibody, followed by microar...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-38222 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Inflammatory Breast Cancer Cells Treated with the Novel Histone Deacetylase Inhibitor, CG-1521
Studies of gene expression profiles using the whole genome wide microarray analysis in SUM149PT cells (ER-, p53mut) and SUM190PT cells (ER-, p53mut) when treated with 5 or 7.5 uM CG-1521 alone and in combination with 10 nM 17beta-estradiol. Comparisons between each treatment group provides evidence ...
ORGANISM(S): Homo sapiens 
2011-04-12 | E-GEOD-28542 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of S. cerevisiae treated with the histone deacetylase inhibitor CG-1521
We set out to identify early changes in gene expression in S. cerevisiae after treatment with the histone deacetylase inhibitor CG-1521. Exponentially growing yeast cells were treated with 50 μM CG-1521 or vehicle control for 1h. The experiment was performed in two independent biological replicates...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-02 | E-GEOD-54300 | biostudies-arrayexpress
TranscriptomicsDilated Cardiomyopathy in Dobermans and Boxers
This study attempts at investigating the changes in cardiac gene expression that occur in Dilated Cardiomyopathy (DCM). DCM in Dobermans and Boxers are the focus of this study. Control heart tissue as well as Pacing tissue used is from mongrel dogs. Keywords: control vs pacing vs disease; strain sp...
ORGANISM(S): Canis lupus familiaris 
2008-05-08 | E-GEOD-11015 | biostudies-arrayexpress
TranscriptomicsThrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: genetic profile and therapeutic effects
Thrombospondin 1 (TSP-1) is an anti-angiogenic matricellular protein with regulatory functions in inflammation and cancer. The type 1 repeats (TSR) domains of TSP-1 have been shown to interact with a wide range of proteins that result in the anti-angiogenic and anti-tumor properties of TSP-1. To eva...
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-32697 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepG2 cells after HDACI treatment
This study compares HEPG2 cells treated with either ethanol(control) or TSA (0.5uM) for 24 hrs. Gene Expression was profiled on HU-133 plus 2.0 arrays Experiment Overall Design: 3 controls vs 3 TSA treated
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-4465 | biostudies-arrayexpress
TranscriptomicsComparison of Mineralizing Synchronous UMR106-01 cells with UMR106-01 cells treated with Mineralization Inhibitor AEBSF
UMR106-01 osteoblastic cells are a model for studying bone mineralization. We have shown that mineralization is temporally synchronized within cultures grown under defined conditions . Cells are plated at time zero and differentiate into osteoblastic phenotype by 64 h later. If an exogenous phosp...
ORGANISM(S): Rattus norvegicus 
2010-11-13 | E-GEOD-21476 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Inflammatory Breast Cancer Cells Treated with the Novel Histone Deacetylase Inhibitor, CG-1521 (Agilent miRNA v12.0)
Studies of gene expression profiles using the whole genomewide microarray analysis of miRNA in SUM149PT cells (ER-, p53mut) and SUM190PT cells (ER-, p53mut) when treated with 5-7.5 µM CG-1521 alone and in combination with 10 nM 17β-Estradiol. Comparisons between each treatment group provides evidenc...
ORGANISM(S): Homo sapiens 
2011-04-12 | E-GEOD-28543 | biostudies-arrayexpress
TranscriptomicsENCODE SUNY RNA Binding Protein GeneST Data for HepG2
RNA Binding Protein immunoprecipitation study for multiple target proteins in HepG2 cell line as part of the ENCODE consortium. Analyzed data tracks available for view on UCSC Genome browser. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome....
ORGANISM(S): Homo sapiens 
2011-09-18 | E-GEOD-31720 | biostudies-arrayexpress
TranscriptomicsENCODE SUNY RNA Binding Protein GeneST Data for K562
RNA Binding Protein immunoprecipitation study for multiple target proteins in K562 cell line as part of the ENCODE consortium. Analyzed data tracks available for view on UCSC Genome browser. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.g...
ORGANISM(S): Homo sapiens 
2011-09-18 | E-GEOD-31717 | biostudies-arrayexpress
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