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UnknownRole of gene polymorphisms in gastric cancer and its precursor lesions: current knowledge and perspectives in Latin American countries.
Latin America shows one of the highest incidence rates of gastric cancer in the world, with variations in mortality rates among nations or even within countries belonging to this region. Gastric cancer is the result of a multifactorial complex process, for which a multistep model of carcinogenesis i...
S-EPMC4000487 | biostudies-literature
UnknownRole of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review.
Gastric cancer remains one of the most common cancers worldwide and one of the leading cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is genetically, cytologically and architecturally more heterogeneous than other gastrointestinal carcinomas. The aberrant ac...
S-EPMC4436943 | biostudies-literature
UnknownTCF7L2 rs7903146 polymorphism is associated with gastric cancer: A case-control study in the Venezuelan population.

Aim

To explore the association between TCF7L2 rs12255372 and rs7903146 single nucleotide polymorphisms (SNPs) and gastric cancer risk in Venezuelan patients.

Methods

We performed a case-control study including 122 paraffin-embedded archived intestinal-type gastric cancer samples and 1...
S-EPMC4968131 | biostudies-literature
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