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The obligate intracellular human pathogen Chlamydia pneumoniae was subjected to dRNA-Seq to gain insights into the transcriptome. The two distinct life cycle forms elementary bodies (EB) and reticulate bodies (RB) were isolated from human Hep2 cell line by differential gradient centrifugation. Total...
ORGANISM(S): Chlamydophila pneumoniae CWL029 
Chlamydia pneumoniae, an obligate intracellular bacterium, causes pneumonia in humans and mice. Toll-like receptors and the key adaptor molecule MyD88 play a critical role in inducing immunity against this microorganism and are crucial to survive the infection. To explore the influence of MyD88 on i...
ORGANISM(S): Mus musculus 
Infection with Chlamydia pneumoniae, a human respiratory pathogen, has been associated with various chronic diseases such as asthma, coronary heart disease and importantly atherosclerosis. Possibly because the pathogen can exist in a persistent form. TNF-a has been reported to induce chlamydial pers...
ORGANISM(S): Homo sapiens 
This experiment is an additional experiment to GSE6688. Mouse macrophages (ANA-1 cells) were infected in vitro with C. pneumoniae with a M.O.I. of 10. Twenty two genes were significantly upregulated. Examples of the most upregulated genes in mouse macrophages after C. pneumoniae infection are serum ...
ORGANISM(S): Mus musculus 
Chlamydia pneumoniae SH511 sequencing
Chlamydia pneumoniae A03 Genome sequencing
Chlamydia pneumoniae B21 Genome sequencing
Chlamydia pneumoniae genome sequencing strain 1979
Chlamydia pneumoniae strain:LSP4 Genome sequencing
Chlamydia pneumoniae strain:WA97001 Genome sequencing
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