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MetabolomicsOral ketone monoester ingestion reduces circulating blood glucose, exogenous carbohydrate oxidation and oxidation efficiency in trained male cyclists when fed 120 g of CHO per hour during exercise

We examined the effects of ketone monoester (KME) and carbohydrate (CHO) co-ingestion on exogenous CHO oxidation, metabolomic responses and exercise capacity. In a randomised repeated-measures design (after a 36 h CHO loading protocol and pre-exercise meal of 12 and 2 g.kg-1, respectively), eight...

2026-04-22 | MTBLS6260 | MetaboLights
MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
ProteomicsInhibition of Alternative Complement Pathway May Cause Secretion of Factor B, Enabling an Early Detection of Pancreatic Cancer
This study aims to elucidate the cellular mechanisms underlying the secretion of factor B (CFB), recognized for its dual role as an early biomarker of pancreatic ductal adenocarcinoma (PDAC) and as the initiating substrate for the alternative complement pathway (ACP), a crucial component of the inna...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD047043 | Pride
Complement factor b Proteomics Adrenomedullin Alternative pathway Pancreatic ductal adenocarcinoma Cancer biomarker Complement factor h 
TranscriptomicsThe gamma secretase inhibitor LLNle induces apoptosis of human GBM tumor initiating cells
Glioblastomas (GBM) are poorly differentiated astrocytic tumors arising in the Central Nervous System (CNS), which despite aggressive treatments are still characterized by a fatal outcome. Several studies have shown the existence of a subpopulation of cells within glioma tumors displaying cancer ste...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14581 | biostudies-arrayexpress
UnknownChronic Alcohol Consumption is Inversely Associated with Insulin Resistance and Fatty Liver in Japanese Males.
Not available
S-EPMC7231020 | biostudies-literature
UnknownModulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models.
Not available
S-EPMC6189172 | biostudies-literature
UnknownRegulation of MIR165/166 by class II and class III homeodomain leucine zipper proteins establishes leaf polarity.
Not available
S-EPMC5081595 | biostudies-literature
UnknownEffects of the Once-Weekly DPP4 Inhibitor Omarigliptin on Glycemic Control in Patients with Type 2 Diabetes Mellitus on Maintenance Hemodialysis: A 24-Week Open-Label, Multicenter Randomized Controlled Study.
Not available
S-EPMC7947073 | biostudies-literature
TranscriptomicsmicroRNA and mRNA expression profiles of human embryonic stem cells treated with activin A
Human embryonic stem (hES) cells have the capacities to propagate for extended periods and to differentiate into cell types from all three germ layers both in vitro and in vivo. These characteristics of self-renewal and pluripotency enable hES cells having the potential to provide an unlimited suppl...
ORGANISM(S): Homo sapiens 
2010-09-10 | E-GEOD-16910 | biostudies-arrayexpress
UnknownStructural brain MRI abnormalities in <i>SCN1A</i>-, <i>SCN2A</i>-, <i>SCN3A</i>-, and <i>SCN8A</i>-related epilepsies: a cohort study.
Not available
S-EPMC12819171 | biostudies-literature
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