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TranscriptomicsProtective Role of IL-10 in Ozone-induced Pulmonary Inflammation
Background: The mechanisms underlying ozone (O3)-induced pulmonary inflammation remain unclear. Interleukin (IL)-10 is an anti-inflammatory cytokine that is known to inhibit inflammatory mediators. Objectives: The current study investigated the molecular mechanisms underlying IL-10-mediated attenua...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-25095 | biostudies-arrayexpress
TranscriptomicsEffect of Nrf2 deletion in postnatal lung development and BPD phenotype in newborn mice
Background: Nrf2 is an essential cytoprotective transcription factor. However, association of Nrf2 in organ development and neonatal disease is rarely examined. Hyperoxia exposure to newborn rodents generates pulmonary phenotypes which resemble bronchopulmonary dysplasia (BPD) of prematurity. Method...
ORGANISM(S): Mus musculus 
2012-05-24 | E-GEOD-29632 | biostudies-arrayexpress
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