Sort   by:  
 Page size 
TranscriptomicsThe nucleoid-associated protein HU controls three regulons that coordinate virulence and general physiology in Salmonella enterica serovar Typhimurium
The regulon of genes controlled by the HU nucleoid-associated proteins was examined in Salmonella enterica serovar Typhimurium (S. Typhimurium). DNA microarrays were used to detect the effect on the bacterial transcriptome of knockout mutations in the hupA, the hupB and in both the hupA and hupB gen...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2011-03-22 | E-GEOD-22860 | biostudies-arrayexpress
MetabolomicsX chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Statin drugs lower blood cholesterol levels for cardiovascular disease prevention. Women are more likely than men to experience adverse statin effects, particularly new-onset diabetes (NOD) and muscle weakness. Here we find that impaired glucose homeostasis and muscle weakness in statin-treated f...

2024-05-23 | MTBLS9677 | MetaboLights
TranscriptomicsDevelopment of distinct gene expression signature in neurons from different regions of the brain
We have performed microarray expression profiling of mouse primary neurons (cortical neurons and granule cell neurons) to model molecular networks and define whether distinct antiviral IFN responses occurred in neurons corresponding to different brain regions. Primary mouse cortical neurons and gran...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-42727 | biostudies-arrayexpress
GenomicsGenomic Analysis of Pediatric Low Grade Gliomas

Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from mutations or duplications in the BRAF kinase in specific subclasses, few genetic driver events are known. Diffuse PLGGs compose a set of uncommon subtypes that exhibit invasive growth and are th...

phs000614.v1.p1 | EGA
GenomicsRNA-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain RNA sequencing
EGAD00001000617 | EGA
GenomicsDATA_SET_ICGC_PedBrain_Tumor_Low-Grade_Astrocytoma_Study - samples
Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood
EGAD00001000271 | EGA
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
GenomicsWGS-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain whole genome sequencing
EGAD00001000616 | EGA
GenomicsWhole-genome sequencing analysis of low-grade astrocytomas within the ICGC PedBrain Tumor Project
In order to investigate the full range of genetic alterations contributing to the tumourigenesis of low-grade astrocytoma, we have conducted a next-generation sequencing-based analysis on a large series of matched tumor-normal pairs. This study, conducted by the International Cancer Genome Consortiu...
EGAS00001000381 | EGA
GenomicsSHH medulloblastoma samples
Sequencing data of human SHH medulloblastoma samples
EGAS00001000607 | EGA
Sort   by:  
 Page size