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TranscriptomicsMicroarray analysis of HK-2 cells treated with cisplatin
Chemotherapeutic use of cisplatin is limited by its severe side effects. In this study, we demonstrated that cisplatin induces cell death in a proximal tubular cell line by suppressing glycolysis- and tricarboxylic acid (TCA)/mitochondria-related genes. HK-2 cells were cultured to confluence in 100m...
ORGANISM(S): Homo sapiens 
2015-06-09 | E-GEOD-69644 | biostudies-arrayexpress
TranscriptomicsPeriostin
We compared transcriptional differences between Periostin siRNA treated and GFP-siRNA treated in OP9 cells using Affymetrix mouse 430_2 array.
ORGANISM(S): Mus musculus 
2012-01-26 | E-MTAB-519 | biostudies-arrayexpress
TranscriptomicsEffect of LPS and LPS-binding protein treatment on RAW 264.4 cells
All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RA...
ORGANISM(S): Mus musculus 
2004-03-04 | E-GEOD-1098 | biostudies-arrayexpress
TranscriptomicsSystems biology analysis of Korean red ginseng effects on Immobilization stressed mice brain
Here we present molecular mechanisms of Korean red ginseng (KRG) on immobilization stresses Keywords: stress response Mice were divided into three groups (3 mice / group): control, stress + no treat, and stress + Korean Red Ginseng (KRG, 100 mg). Stress + KRG group were given KRG 100 mg orally for...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-12656 | biostudies-arrayexpress
TranscriptomicsMajor Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), anti-CD40 (CD40L), LPS, and, to a l...
ORGANISM(S): Mus musculus 
2004-12-08 | E-GEOD-2050 | biostudies-arrayexpress
TranscriptomicsRAW264.7 cells were treated with KDO, IFN beta and 8Br
RAW 264.7 cells were stimulated with KDO (100 ng/ml), IFN-β (300 pM) and/or 8-Br 100 μM. These ligands were applied individually or in combination with KDO for 60 min and 120 min. Total RNA was extracted using TriPure (Roche) following its protocol. Keywords: designed RAW 264.7 cells were stimulat...
ORGANISM(S): Mus musculus 
2008-06-28 | E-GEOD-11449 | biostudies-arrayexpress
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