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TranscriptomicsDo different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons
The complexity of events associated with age-related memory loss (ARML) cannot be overestimated. The problem is further complicated by the enormous diversity of neurons in the CNS and even synapses of one neuron within a neural circuit. Large-scale single-neuron analysis is not only challenging but ...
ORGANISM(S): Aplysia californica 
2010-05-20 | E-GEOD-18783 | biostudies-arrayexpress
GenomicsCholinergic Signaling Modulates Intestinal Pathophysiology in a Drosophila Model of Cystic Fibrosis
Cholinergic Signaling Modulates Intestinal Pathophysiology in a Drosophila Model of Cystic Fibrosis
PRJNA1281518 | ENA
TranscriptomicsAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
This SuperSeries is composed of the following subset Series: GSE34886: Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity [expression profiling] GSE34887: Acute depletion of Tet1-dependent 5-hydroxymethylcy...
ORGANISM(S): Mus musculus 
2012-01-04 | E-GEOD-34267 | biostudies-arrayexpress
GenomicsA Minimal Transcriptional Footprint of Endogenous Cholinergic Signaling in the Hippocampus After Acute and Repeated Forced Swim Stress
A Minimal Transcriptional Footprint of Endogenous Cholinergic Signaling in the Hippocampus After Acute and Repeated Forced Swim Stress
PRJNA1525939 | ENA
ProteomicsLC-MS/MS data of Tinospora cordifolia
Tinospora cordifolia has been used for thousands of years to treat various health conditions, including neurodegenerative diseases. The study aimed to elucidate the mechanism of action and protein targets of T. cordifolia in the context of Alzheimers disease through untargeted metabolomics and netwo...
ORGANISM(S): Tinospora Cordifolia (ncbitaxon:285590) 
2024-11-04 | MSV000096283 | MassIVE
GenomicsCholinergic regulation of thymocyte negative selection
Cholinergic regulation of thymocyte negative selection
PRJNA1084716 | ENA
TranscriptomicsAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity [expression profiling]
The TET family of FE(II) and 2-oxoglutarate-dependent enzymes (Tet1/2/3) promote DNA demethylation by converting 5-methylcytosine to 5-hydroxymethylcytosine (5hmC), which they further oxidize into 5-formylcytosine and 5-carboxylcytosine. Tet1 is robustly expressed in mouse embryonic stem cells (mESC...
ORGANISM(S): Mus musculus 
2012-01-06 | E-GEOD-34886 | biostudies-arrayexpress
GenomicsAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity [MRE-seq]
The TET family of FE(II) and 2-oxoglutarate-dependent enzymes (Tet1/2/3) promote DNA demethylation by converting 5-methylcytosine to 5-hydroxymethylcytosine (5hmC), which they further oxidize into 5-formylcytosine and 5-carboxylcytosine. Tet1 is robustly expressed in mouse embryonic stem cells (mESC...
ORGANISM(S): Mus musculus 
2012-01-06 | E-GEOD-34887 | biostudies-arrayexpress
UnknownExercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling.
Not available
S-EPMC11572510 | biostudies-literature
UnknownCholinergic neuroplasticity in asthma driven by TrkB signaling.
Not available
S-EPMC7302963 | biostudies-literature
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