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ProteomicsEnhancing the chondrogenic potential of chondrogenic progenitor cells by deletion of RAB5C
Osteoarthritis (OA) is the most prevalent chronic joint disease that affects a majority of the elderly. Chondrogenic progenitor cells (CPCs) reside in late stage OA cartilage tissue, producing a fibrocartilagenous extra-cellular matrix and can be manipulated in-vitro, to deposit proteins of healthy ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021785 | Pride
Chondrogenic progenitor cells  rab5c  osteoarthritis 
TranscriptomicsGene expression and alternative splicing data from human cartilage endplate-derived stem cells
Low back pain (LBP) is one of the most prevalent conditions which need medical advice and result in chronic disabilities. Degenerative disc disease (DDD) is a common reason for LBP. A lot of researchers think that CEP degeneration play critical roles in the initiation and development of DDD. In rece...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-63897 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human meenchymal stem cells expanded for up to seven passages with our without fibroblast growth factor
Fibroblast growth factor-2 delays the loss of chondrogenic potential in adult bone marrow-derived mesenchymal stem cells; We compared human mesenchymal stem cells (hMSCs), expanded long-term with and without fibroblast growth factor (FGF) supplementation, with respect to their proliferation rate, an...
ORGANISM(S): Homo sapiens 
2009-11-10 | E-GEOD-14828 | biostudies-arrayexpress
TranscriptomicsRNA-Seq Analysis Reveals Different Dynamics of Differentiation of Human Dermis- and Adipose-derived Stromal Stem Cells
Background: Tissue regeneration and recovery in the adult body depends on self-renewal and differentiation of stem and progenitor cells. Mesenchymal stem cells (MSCs) that have the ability to differentiate into various cell types, have been isolated from the stromal fraction of virtually all t...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-37521 | biostudies-arrayexpress
TranscriptomicsFetal mesenchymal stromal cells differentiating towards chondrocytes acquire a gene expression profile resembling human growth plate cartilage.
We used human fetal bone marrow-derived mesenchymal stromal cells (hfMSCs) differentiating towards chondrocytes as an alternative model for the human growth plate (GP). Our aims were to study gene expression patterns associated with chondrogenic differentiation to assess whether chondrocytes derived...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-40942 | biostudies-arrayexpress
ModelsSchittler2010 - Cell fate of progenitor cells, osteoblasts or chondrocytes
Schittler2010 - Cell fate of progenitor cells, osteoblasts or chondrocytes Mathematical model describing the mechanism of differentiation of mesenchymal stem cells to bone (osteoblasts) or cartilage (chondrocytes) cells. This model is described in...
2024-09-02 | BIOMD0000000493 | BioModels
TranscriptomicsRNA-seq of ATDC5 cell-line with scrambled or Sox9 knockdown at 2 hours and 7 days in chondrocgenic differentiation.
Introduction: In addition to the well-known cartilage extracellular matrix-related expression of Sox9, we demonstrated that chondrogenic differentiation of progenitor cells is driven by a sharply defined bi-phasic expression of Sox9: an immediate early and a late (extracellular matrix associated) ph...
ORGANISM(S): Mus musculus 
2021-06-01 | E-MTAB-10333 | biostudies-arrayexpress
GenomicsLoss of Grem1-lineage chondrogenic progenitor 1 cells causes osteoarthritis
Loss of Grem1-lineage chondrogenic progenitor 1 cells causes osteoarthritis
PRJNA1014429 | ENA
UnknownTendon progenitor cells in injured tendons have strong chondrogenic potential: the CD105-negative subpopulation induces chondrogenic degeneration.
Not available
S-EPMC4245375 | biostudies-literature
GenomicsHuman adipose tissue-derived mesenchymal progenitor cells induced toward adipogenic, chondrogenic, or osteogenic induction fates.
Human adipose tissue-derived mesenchymal progenitor cells induced toward adipogenic, chondrogenic, or osteogenic induction fates.
PRJNA814320 | ENA
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