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TranscriptomicsAntioxidant response gene expression in the bronchial airway epithelial cells of smokers at risk for lung cancer
Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. This study examines the relationship between gene expression vari...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-19027 | biostudies-arrayexpress
GenomicsIdentification of Novel NRF2-Regulated Genes by ChIPSeq
Cellular oxidative and electrophilic stress triggers a protective response in mammals regulated by NRF2 (nuclear factor (erythroid-derived) 2-like; NFE2L2) binding to DNA-regulatory sequences near stress responsive genes. Studies using Nrf2-deficient mice suggest that hundreds of genes may be regula...
ORGANISM(S): Homo sapiens 
2012-06-18 | E-GEOD-37589 | biostudies-arrayexpress
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