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UnknownMethylglyoxal Levels in Human Colorectal Precancer and Cancer: Analysis of Tumor and Peritumor Tissue.
Colorectal cancer (CRC) is one of the most common cancers worldwide and its incidence is increasing; therefore, an understanding of its oncogenic mechanisms is critical for improving its treatment and management. Methylglyoxal (MGO) has a highly reactive aldehyde group and has been suggested to play...
S-EPMC8708054 | biostudies-literature
UnknownEmulating Hyperspectral and Narrow-Band Imaging for Deep-Learning-Driven Gastrointestinal Disorder Detection in Wireless Capsule Endoscopy.
Diagnosing gastrointestinal disorders (GIDs) remains a significant challenge, particularly when relying on wireless capsule endoscopy (WCE), which lacks advanced imaging enhancements like Narrow Band Imaging (NBI). To address this, we propose a novel framework, the Spectrum-Aided Vision Enhancer (SA...
S-EPMC12467974 | biostudies-literature
UnknownEfficacy of Prenatal Yoga in the Treatment of Depression and Anxiety during Pregnancy: A Systematic Review and Meta-Analysis.
Women commonly suffer from depression during pregnancy. For reducing depression, yoga seems to be more suitable for pregnant women than other physical activities because of its low exercise intensity. The objective of this study was to assess the efficacy of prenatal yoga on the treatment of depress...
S-EPMC9105819 | biostudies-literature
UnknownValidation of an Automated Cardiothoracic Ratio Calculation for Hemodialysis Patients.
Cardiomegaly is associated with poor clinical outcomes and is assessed by routine monitoring of the cardiothoracic ratio (CTR) from chest X-rays (CXRs). Judgment of the margins of the heart and lungs is subjective and may vary between different operators.

Methods

Patients aged > 19 years in o...
S-EPMC10137564 | biostudies-literature
UnknownCOL11A1 confers chemoresistance on ovarian cancer cells through the activation of Akt/c/EBPβ pathway and PDK1 stabilization.
Chemoresistance to anticancer drugs substantially reduces survival in epithelial ovarian carcinoma (EOC). Here, microarray analysis showed that collagen type XI alpha 1 (COL11A1) is a chemotherapy response-associated gene. Chemoresistant cells expressed higher COL11A1 and c/EBPβ than chemosensitive ...
S-EPMC4695149 | biostudies-literature
UnknownA high resolution computer tomography scoring system to predict culture-positive pulmonary tuberculosis in the emergency department.
This study evaluated the use of high-resolution computed tomography (HRCT) to predict the presence of culture-positive pulmonary tuberculosis (PTB) in adult patients with pulmonary lesions in the emergency department (ED). The study included a derivation phase and validation phase with a total of 8,...
S-EPMC3984117 | biostudies-literature
UnknownNontuberculous mycobacterial infection is associated with increased respiratory failure: a nationwide cohort study.

Background and purpose

Population study on relationship between nontuberculous mycobacterial (NTM) infection and respiratory failure (RF) is limited. This study evaluated the RF risk, including acute respiratory failure (ARF), chronic respiratory failure (CRF) and ARF on CRF, in patients wit...
S-EPMC4053398 | biostudies-literature
UnknownComparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment.
Epithelial ovarian carcinoma (EOC) is the most lethal gynecological malignancy. Herein, we sought to determine the efficacy of phosphoinositide 3-kinase (PI3K)/Akt inhibition using three AZD compounds in a NOD-SCID xenograft mouse model and Akt regulation in a panel of eight ovarian cancer cell line...
S-EPMC7063971 | biostudies-literature
UnknownEpigenetic silencing of the NR4A3 tumor suppressor, by aberrant JAK/STAT signaling, predicts prognosis in gastric cancer.
While aberrant JAK/STAT signaling is crucial to the development of gastric cancer (GC), its effects on epigenetic alterations of its transcriptional targets remains unclear. In this study, by expression microarrays coupled with bioinformatic analyses, we identified a putative STAT3 target gene, NR4A...
S-EPMC4985659 | biostudies-literature
UnknownEndoscopic full-thickness resection using double endoscope-assisted snare traction for a large exophytic gastric subepithelial lesion.
Video 1Endoscopic full-thickness resection using double endoscope-assisted snare traction facilitates precise resection of a large exophytic gastric subepithelial lesion.
S-EPMC10928133 | biostudies-literature
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