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UnknownLong-term metabolic effects of non-nutritive sweeteners.
Not available
S-EPMC11347859 | biostudies-literature
MetabolomicsAutomated, Parallel Mass Spectrometry Imaging and Structural Identification of Lipids
We report a method that enables automated data-dependent acquisition of lipid tandem mass spectrometry data in parallel with a high-resolution mass spectrometry imaging experiment. The method does not increase the total image acquisition time and is combined with automatic structural assignment. Thi...
2018-05-21 | MTBLS597 | MetaboLights
TranscriptomicsUncovering Genes and Regulatory Pathways Related to Urinary Albumin Excretion in Mice
Identifying the genes underlying quantitative trait loci (QTL) for disease has proven difficult, mainly due to the low resolution of the approach and the complex genetics involved. However, recent advances in bioinformatics and the availability of genetic resources now make it possible to narrow the...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-23310 | biostudies-arrayexpress
TranscriptomicsSmall Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Hepatocellular Carcinoma Huh-7 Cells
Screening small molecules and drugs for activity to modulate alternative splicing, we found that amiloride, distinct from four other intracellular pH-affecting analogues, could “normalize” the splicing of BCL-X, HIPK3 and RON/MISTR1 transcripts in human hepatocellular carcinoma Huh-7 cells. To eluci...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-24581 | biostudies-arrayexpress
TranscriptomicsPre-Collaborative Cross liver gene expression
The Collaborative Cross (CC) recombinant inbred panel was conceived as an ideal resource for mammalian system genetics. The pre-CC is a proof-of-concept experiment involving CC lines that have undergone at least five generations of inbreeding. Siblings from these lines were each involved in one of...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-22297 | biostudies-arrayexpress
TranscriptomicsPla2g12b and Hpn are Genes Identified by Mouse ENU Mutagenesis that affect HDL cholesterol
Despite considerable progress understanding genes that affect the HDL particle, its function, and cholesterol content, genes identified to date explain only a small percentage of the genetic variation. We used N-ethyl-N-nitrosourea mutagenesis in mice to discover novel genes that affect HDL choleste...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-37902 | biostudies-arrayexpress
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