Chp1 - OmicsDI

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Tags

xref:ArrayExpress:E-MTAB-3705 (1)
xref:PubMed:31255284 (1)
xref:PubMed:42258092 (1)
xref:PubMed:36542473 (1)
xref:PubMed:29237752 (1)
xref:PubMed:38360885 (1)

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MS data for Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

Cotranslational protein folding depends on general chaperones that engage highly diverse nascent chains at the ribosomes. It is not clear how this promiscuous mechanism ensure efficient production of challenging clients such as highly expressed proteins. Here we find that the biogenesis of the abund...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2024-06-16 | PXD043391 | Pride

Nuclear aconitase regulates heterochromatin formation by interacting with Chp1

Aconitase is a highly conserved metabolic enzyme for TCA cycle. In Schizosaccharomyces pombe, an aconitase (Aco2) is localized in both mitochondria and the nucleus, apart from an exclusively mitochondrial one (Aco1). We investigated the role of nuclear Aco2, and present evidences that it interacts w...

ORGANISM(S): Schizosaccharomyces pombe

2020-03-25 | GSE101804 | GEO

CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.

Not available

S-EPMC6450717 | biostudies-literature

Structure and mechanism of the human NHE1-CHP1 complex.

Not available

S-EPMC8190280 | biostudies-literature

Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.

Not available

S-EPMC5775069 | biostudies-literature

CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis.