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TranscriptomicsJnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and identify the cell-type involved ...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-40041 | biostudies-arrayexpress
UnknownClofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: results from the CLASSIC I Trial.
Not available
S-EPMC4874149 | biostudies-literature
UnknownMultitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis.
Not available
S-EPMC9958016 | biostudies-literature
ProteomicsT.brucei - Whole organism, sequence+MS2 intensity (Urbaniaketal,jproteomeres2013)
abundance based on sequence+MS2 intensity, Interaction consistency score: 17.7, Coverage: 56
ORGANISM(S): 5691 
2013-00-00 | 4092869827 | PAXDB
ProteomicsT.brucei - Whole organism, sequence+MS2 intensity (Urbaniaketal,jproteomeres2013)
abundance based on sequence+MS2 intensity, Interaction consistency score: 17.4, Coverage: 56
ORGANISM(S): 5691 
2013-00-00 | 4181687758 | PAXDB
UnknownExpert-based physical activity guidelines for metabolic and bariatric surgery patients: a systematic review of randomized controlled trials.
Not available
S-EPMC12444777 | biostudies-literature
GenomicsLinking genes, genomic instability and molecular subgroups in medulloblastoma
Brain tumors are the second most common pediatric cancer and carry the highest mortality rates in this age group. Medulloblastoma is the most frequent malignant brain tumor of childhood. Recent studies indicate that medulloblastoma comprises at least four sub-entities (SHH-signaling, WNT-signali...
EGAS00001000085 | EGA
UnknownA Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Not available
S-EPMC7556703 | biostudies-literature
MetabolomicsSuccinate accumulation drives ischaemia-reperfusion injury during organ transplantation
During heart transplantation, storage in cold preservation solution is thought to protect the organ by slowing metabolism; by providing osmotic support; and by minimising ischaemia-reperfusion (IR) injury upon transplantation into the recipient. Despite its widespread use, our understanding of the m...
2019-09-20 | MTBLS1085 | MetaboLights
GenomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [ChIP-Seq]
CTCF and CTCFL DNA binding profile in CTCFL induced and non-induced ES cells.CTCF is a highly conserved and essential zinc finger protein that in conjunction with cohesin organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The function of CTCFL or BORIS, the tes...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-34094 | biostudies-arrayexpress
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