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TranscriptomicsCTL-OA-OP human IT PF Bone - CompuGen H19K microarray study
Aims of study: (1) To identify systemic differences in osteoarthritic (OA) bone that contribute to OA pathogenesis. (2) Identify novel osteoporotic (OP) bone-related disease genes. Study involved comparison of trabecular bone extracted from the intertrochanteric (IT) region of the proximal femur (PF...
ORGANISM(S): Homo sapiens 
2008-01-14 | E-GEOD-8406 | biostudies-arrayexpress
TranscriptomicsSeminal plasma and transforming growth factor-β regulate gene expression in human Ect1 ectocervical epithelial cells
In this study we examined the influence of seminal plasma on gene expression in human Ect1 ectocervical epithelial cells, and the extent to which recombinant TGFβ3 elicits comparable changes. Ect1 cells were incubated with recombinant human TGFβ3 (5 ng/ml), 10% pooled human seminal plasma (v/v), or ...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-35830 | biostudies-arrayexpress
TranscriptomicsThe ets transcription factor ELF5 suppresses the estrogen sensitive phenotype and contributes to antiestrogen resistance in luminal breast cancer. [mouse]
The ets transcription factor ELF5 specifies the differentiation of mammary progenitor cells to establish the milk-secreting lineage. ER- and poor prognosis basal breast cancers arise from this progenitor cell and these cancers express high levels of Elf5. Knockdown of ELF5 expression in basal breast...
ORGANISM(S): Mus musculus 
2014-01-13 | E-GEOD-30406 | biostudies-arrayexpress
GenomicsA Genomic History of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterised. We generated high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25...
EGAS00001001766 | EGA
TranscriptomicsDifferential gene expression in resting human skeletal muscle of sedentary and highly-trained individuals.
We used gene microarray analysis to compare the global expression profile of genes involved in adaptation to exercise training in skeletal muscle from chronically strength/resistance trained (ST), endurance trained (ET) and untrained control subjects (Con). Resting skeletal muscle samples (~100mg) ...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-9405 | biostudies-arrayexpress
Transcriptomicsembryo A-class motor neurons tiling array
modENCODE_submission_654 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23278 | biostudies-arrayexpress
Transcriptomicsembryo germline precursor cells tiling array
modENCODE_submission_661 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23285 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling in human macrophages under immunogenic treatments in vitro
MicroRNAs (miRs) contribute to both neuronal and immune cell fate, but their involvement in inter-tissue communication remained unexplored. The brain, via vagal secretion of acetylcholine (ACh), suppresses peripheral inflammation by intercepting cytokine production; therefore, we predicted that micr...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-19094 | biostudies-arrayexpress
TranscriptomicsTLR4 Signaling Is a Major Mediator of the Female Tract Response to Seminal Fluid in Mice
To examine the effect of seminal fluid on the whole genome expression profile of endometrial tissue following mating, RNA was extracted from endometrial tissue collected 8 h after CBAF1 females were mated with intact Balb/c males and compared to RNA from endometrial tissue of females mated with semi...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-70401 | biostudies-arrayexpress
Transcriptomicsembryo panneural tiling array
modENCODE_submission_455 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23245 | biostudies-arrayexpress
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