Christopher Mark M

Show results for

Genomics (95)
Transcriptomics (57)
Unknown (41)
Proteomics (23)
Metabolomics (6)
Genomic (2)
Other (1)
Multiomics (1)

Organisms

Homo sapiens (114)
Mus musculus (24)
Arabidopsis thaliana (7)
Saccharomyces cerevisiae (3)
Dictyostelium discoideum (3)
Rattus norvegicus (2)
Canis lupus (1)
human gut metagenome (1)
Euphorbia esula (1)
Populus x canadensis (1)
Papio anubis (1)
Arabidopsis lyrata (1)
Pan troglodytes (1)
Daphnia magna (1)
Schizosaccharomyces pombe (1)
Pseudomonas aeruginosa (1)
Escherichia coli (1)

Repository

EGA (79)
biostudies-arrayexpress (73)
pride (11)
MassIVE (10)
GNPS (3)
MetaboLights (3)
dbGaP (2)
GPMDB (1)
PanoramaPublic (1)
PeptideAtlas (1)

Tissue

Dental pulp (2)
Blood platelet (1)
JURKAT cell (1)
Pancreas (1)
Platelet (1)
T cell (1)

Disease

Pulmonary arterial hypertension (1)
Alpha-1 antitrypsin deficiency-related emphysema (1)
Not Available (1)
Acute lymphocytic leukemia (1)
Platelet storage pool deficiency (1)

Technology Type

Mass Spectrometry (11)
Illumina 15K (8)
Shotgun proteomics (6)
Affinity purification coupled with mass spectrometry proteomics (4)
Mass spectrometry (3)
Illumina HiSeq 2000 (2)
AB SOLiD 4 System, Illumina HiSeq 2500, Illumina HiSeq 2000, AB SOLiD System 3.0 (1)
Affymetrix 6.0 (1)
Illumina 1.2M, Affymetrix 6.0 (1)
Illumina 1.2M, Affymetrix 6.0, Affymetrix 6.0 - CHIAMO (1)
Illumina 1.2M, Illumina 610K Quad, Affymetrix 6.0 (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500, ILLUMINA (1)
Illumina HumanExome-12v1_A-GenCall, zCall, GenoSNP, - Illuminus (1)
Illumina Omni 2.5, Illiumina Omni 2.5 (1)
Illumina_670k - Illuminus, Affymetrix 6.0, Illumina 1.2M (1)
Bottom-up proteomics (1)

Instrument Platform

Orbitrap Fusion Lumos (5)
Illumina HiSeq 2500 (3)
Orbitrap Fusion (3)
AB SOLiD 4 System (2)
Illumina HiSeq 4000 (2)
Orbitrap Exploris 480 (2)
6520A Quadrupole Time-of-Flight LC/MS (2)
LTQ Orbitrap (2)
Scanning hardware (1)
Instrument (1)
Exactive Plus (1)
Q Exactive Plus (1)
Gas Chromatography MS - (1)
Liquid Chromatography MS - negative - reverse phase (1)
Q Exactive (1)
Xevo G2 QTOF (Waters) (1)

Publication Date

2010 (19)
2014 (14)
2015 (10)
2011 (8)
2021 (7)
2013 (7)
2012 (7)
2019 (5)
2007 (4)
2022 (4)
2008 (3)
2020 (3)
2023 (3)
2017 (2)
2016 (2)
2018 (2)
2025 (1)

CHEBI ID

CHEBI:16359 (3)
CHEBI:15356 (2)
CHEBI:15428 (2)
CHEBI:15760 (2)
CHEBI:15887 (2)
CHEBI:16411 (2)
CHEBI:16449 (2)
CHEBI:16755 (2)
CHEBI:16765 (2)
CHEBI:16811 (2)
CHEBI:17822 (2)
CHEBI:18186 (2)
CHEBI:18237 (2)
CHEBI:22660 (2)
CHEBI:24898 (2)
CHEBI:25017 (2)
CHEBI:25094 (2)
CHEBI:26271 (2)
CHEBI:26986 (2)
CHEBI:27266 (2)
CHEBI:27897 (2)
CHEBI:28044 (2)
CHEBI:28484 (2)
CHEBI:28834 (2)
CHEBI:30745 (2)
CHEBI:30746 (2)
CHEBI:32980 (2)
CHEBI:43580 (2)
CHEBI:59783 (2)
CHEBI:60645 (2)

Metabolite Name

(9Z,12Z)-(8R)-8-Hydroperoxyoctadeca-9,12-dienoic acid (HPODE) (1)
1-methylguanidine (1)
1-methylhistidine (1)
1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4) (1)
1-palmitoyl-2-oleoyl-GPC (16:0/18:1) (1)
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)* (1)
1-palmitoyl-2-stearoyl-GPC (16:0/18:0) (1)
1-palmitoyl-GPA (16:0) (1)
12,13-DiHOME (1)
15-methylpalmitate (1)
16-hydroxypalmitate (1)
17-methylstearate (1)
2'-deoxyadenosine (1)
2'-deoxyadenosine 5'-diphosphate (1)
2'-deoxyadenosine 5'-monophosphate (1)
2'-deoxycytidine (1)
2'-deoxycytidine 5'-monophosphate (1)
2'-deoxyguanosine (1)
2'-deoxyinosine (1)
2'-deoxyuridine (1)
2,3-dihydroxyisovalerate (1)
2-aminoadipate (1)
2-aminoheptanoate (1)
2-hydroxy-3-methylvalerate (1)
2-hydroxyadipate (1)
2-hydroxybutyrate/2-hydroxyisobutyrate (1)
2-hydroxyphenylacetate (1)
2-isopropylmalate (1)
2-piperidinone (1)
2-pyrrolidinone (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (3)
N6-dimethyl-L-lysine (2)
4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (32)
ChIP-seq (11)
RNA-seq of coding RNA (9)
Methylation profiling by high throughput sequencing (5)
Comparative genomic hybridization by array (3)
ChIP-chip by tiling array (2)
Genotyping by array (2)
Other (2)
RNA-seq of non coding RNA (2)
Unknown experiment type (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
RIP-seq (1)

Release Date

2010 (19)
2014 (14)
2015 (12)
2012 (9)
2013 (8)
2011 (8)
2024 (6)
2020 (6)
2021 (4)
2016 (4)
2007 (4)
2025 (4)
2018 (4)
2019 (3)
2017 (3)
2008 (3)
2022 (2)
2023 (1)

Lab affiliation

Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada (3)
Dept. of Biochemistry & Molecular Biology, Complex Carbohydrate Research Center, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, Dept. of Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 USA (2)
Professor and Tier 1 Canada Research Chair in Proteinase Proteomics and Systems Biology at the University of British Columbia, Centre for Blood Research (2)
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation (1)
Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada. (1)
Dept. of Biochemistry & Molecular Biology, Complex Carbohydrate Research Center, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, United States Dept. of Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States (1)
University of British Columbia (1)

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Epigenetic regulation by chromatin activation mark H3K4me3 in primate progenitor cells within adult neurogenic niche [ChIP-seq]

Histone 3 lysine 4 trimethylation (H3K4me3) is known to be associated with transcriptionally active or poised genes and required for postnatal neurogenesis within the subventricular zone (SVZ) in the rodent model. Previous comparisons have shown significant correlation between baboon (Papio anubis) ...

ORGANISM(S): Papio anubis

2014-07-16 | E-GEOD-58530 | biostudies-arrayexpress

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq)

Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain. Genome-wide analysis showed a novel chromatin signature for this mark. Reducing the levels of the H3...

ORGANISM(S): Mus musculus

2013-07-18 | E-GEOD-48962 | biostudies-arrayexpress

Interplay Between Active Chromatin Marks and RNA-directed DNA Methylation in Arabidopsis thaliana

DNA methylation is an epigenetic mark that is associated with transcriptional repression of transposable elements and protein coding genes. Conversely, transcriptionally active regulatory regions are strongly correlated with histone 3 lysine 4 di- and trimethylation (H3K4m2/3). We previously showed ...

ORGANISM(S): Arabidopsis thaliana

2013-11-01 | E-GEOD-49090 | biostudies-arrayexpress

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (ChIP-seq)

ORGANISM(S): Mus musculus

2013-07-18 | E-GEOD-48960 | biostudies-arrayexpress

Transcription profiling of human peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension

Microarray analysis of peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension.

ORGANISM(S): Homo sapiens

2007-09-21 | E-GEOD-703 | biostudies-arrayexpress

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights

A High-Fat Diet and NAD+ Rescue Premature Aging in Cockayne Syndrome

Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csbm/m mice were given a high-fat, caloric-restricted or resveratrol-supplemented diet. The high-fat diet rescued the p...

ORGANISM(S): Mus musculus

2014-12-22 | E-GEOD-62194 | biostudies-arrayexpress

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

Not available

S-EPMC4981979 | biostudies-literature

SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma.

Not available

S-EPMC4534524 | biostudies-literature

Chromatin immunoprecipitation with next generation sequencing (ChIP-seq) of H3K27ac in primary human macrophages and foam cells

We report the enhancer landscape in primary human macrophages and foam cells using ChIP-seq for the H3K27ac histone mark CD14+ monocytes were isolated from the blood of 2 healthy male volunteers. Monocytes were differentiated into macrophages by culture for 7 days with 50ng/ml macrophage colony stim...

ORGANISM(S): Homo sapiens

2015-04-08 | E-GEOD-54972 | biostudies-arrayexpress

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