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MetabolomicsIdentification of Biomarkers Using Metabolomics: From Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis to Gastric Cancer

Gastric cancer (GC) is a severe malignancy characterized by late diagnosis, poor prognosis and low survival rates. Its progression is often linked to chronic non-atrophic gastritis (CNAG) and chronic atrophic gastritis (CAG), which show atypical symptoms. Identifying biomarkers for CNAG, CAG and ...

2026-09-29 | MTBLS12186 | MetaboLights
MetabolomicsNMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a high prevalence. Exploring of the underlying mechanism and potential biomarkers is of significant importance for CAG. In the present work, 1H NMR-based metabonomics with correlative analysis was performed to an...
2016-08-31 | MTBLS340 | MetaboLights
TranscriptomicsResponse of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis
This SuperSeries is composed of the following subset Series: GSE16390: Response of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 1 GSE16439: Response of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chroni...
ORGANISM(S): Mus musculus 
2009-10-26 | E-GEOD-16440 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MALT lymphoma and chronic gastritis tissue from the same patients
21 Tissue samples of gastric MALT lymphoma were compared by cDNA microarray studies with chronic gastritis tissues from the same patient. From each patient, multiple mucosal biopsies of the stomach were taken both from i) the macroscopically infiltrated area and ii) distant from the lymphoma. For co...
ORGANISM(S): Homo sapiens 
2007-07-24 | E-MEXP-1168 | biostudies-arrayexpress
TranscriptomicsExpression data from Helicobacter pylori isolates infecting a gastric epithelial progenitor cell line
Helicobacter pylori clinical isolates can establish themselves in gastric epithelial stem cells and this interaction may have implications for gastric tumorigenesis. Mouse gastric epithelial progenitor cells (mGEPs) were infected for 24hrs with Helicobacter pylori clinical isolates Kx1 and Kx2. Kx1 ...
ORGANISM(S): Helicobacter pylori 
2010-05-26 | E-GEOD-10261 | biostudies-arrayexpress
TranscriptomicsResponse of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 2
Helicobacter pylori infection is associated with development of gastric adenocarcinoma in a subset of infected humans, especially those that develop an antecedent condition, chronic atrophic gastritis (ChAG) characterized by loss of acid-producing parietal cells. Studies in a gnotobiotic transgenic ...
ORGANISM(S): Helicobacter pylori 
2010-06-20 | E-GEOD-16439 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 1
Helicobacter pylori infection is associated with development of gastric adenocarcinoma in a subset of infected humans, especially those that develop an antecedent condition, chronic atrophic gastritis (ChAG) characterized by loss of acid-producing parietal cells. Studies in a gnotobiotic transgenic ...
ORGANISM(S): Mus musculus 
2009-11-11 | E-GEOD-16390 | biostudies-arrayexpress
TranscriptomicsHelicobacter pylori pathogenic mechanism
Helicobacter pylori infection reprograms host gene expression and influences various cellular processes, which have been investigated by cDNA microarray in vitro culture cells and in vivo patients of the chronic abdominal complaint. In this study，the effects of H. pylori infection on host gene expre...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-30042 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis reveals the molecular details of atrophic gastritis in Helicobacter pylori infected corpus mucosa
The majority of gastric cancer cases are believed to be caused by chronic infection with the bacterium Helicobacter pylori, and atrophic corpus gastritis is a predisposing condition to gastric cancer development. We aimed to increase understanding of the molecular details of atrophy by performing a ...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-27411 | biostudies-arrayexpress
TranscriptomicsmiRNA sequencing data from patients with non-active gastritis, chronic active gastritis and precursor lesions of gastric cancer.
Helicobacter pylori infection can induce gastric pathologies ranging from chronic gastritis to peptic ulcers and gastric cancer. Individuals´ response to H. pylori infection is complex and it depends on a combination of environmental factors, genetic background, host response and strain virulence. T...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8890 | biostudies-arrayexpress
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