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TranscriptomicsGene Expression Profiling of siRNA Knock-Down of Six1, Six4 and Myogenin in C2C12
Six1, Six4 and Myogenin are transcription factors that are known to be required for skeletal myogenesis. Currently, very little is known about the genes targeted by Six1 and Six4. Gene expression profiling when one or both transcription factors were knock-down by siRNA was performed to identify gene...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-19967 | biostudies-arrayexpress
TranscriptomicsRNA-Seq profiling of C2C12 cells with exogenous expression of Mef2Da1 and Mef2Da2
Although splicing occurs in most multi-exon genes, the generation of distinct isoforms through the alternate use of mutually exclusive exons is less prevalent. As exon-switching events have the potential to give rise to isoforms with different cellular functions, we have explored the role of the mus...
ORGANISM(S): Mus musculus 
2013-06-03 | E-GEOD-46363 | biostudies-arrayexpress
GenomicsComparative analysis of TAL1 binding in TSA-treated versus non-treated Endothelial Colony Forming Cells (ECFCs)
Endothelial progenitors represent one of the most promising cell-based strategies for vascular repair of ischemic tissue damage, including limb ischemia, myocardial infarction and stroke. We have shown that the transcription factor TAL1 regulates a transcription program that drives the migration and...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53423 | biostudies-arrayexpress
GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing of primary myoblasts from mice with a satellite cell specific knockout of the histone demthylase UTX/KDM6A
The KDM6 histone demethylases (UTX/KDM6A and JMJD3/KDM6B) mediate removal of repressive histone H3K27me3 marks to establish transcriptionally permissive chromatin. Loss of UTX in female mice is embryonic lethal. Unexpectedly, male UTX-null mice escape embryonic lethality due to expression of UTY, a ...
ORGANISM(S): Mus musculus 
2016-03-22 | E-GEOD-69968 | biostudies-arrayexpress
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
GenomicsTAL1 in human Endothelial Colony-Forming Cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-44546 | biostudies-arrayexpress
UnknownLong-Term Post-Stroke Cognition in Patients With Minor Ischemic Stroke is Related to Tract-Based Disconnection Induced by White Matter Hyperintensities.
Not available
S-EPMC11770330 | biostudies-literature
TranscriptomicsExpression analysis of pre-phenotype dt27J mouse dorsal root ganglia
Loss of function of dystonin cytoskeletal linker proteins causes neurodegeneration in the sensory ataxia, dystonia musculorum (dt). While much investigation has focused on understanding dt pathology, divergent functions of dystonin isoforms are still unknown. Here, we highlight a novel function of...
ORGANISM(S): Mus musculus 
2012-02-23 | E-GEOD-30960 | biostudies-arrayexpress
UnknownCharacterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-α.
Not available
S-EPMC4569087 | biostudies-literature
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