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ProteomicsA new role for the DEAD-box RNA helicase DDX3 in co-translational protein quality control
DEAD-box RNA helicases are central players in RNA metabolism, however, their role in translation regulation is largely unexplored in parasitic protozoa. Here, we have investigated the role of DDX3 RNA helicase in ribosome-associated protein quality control in Leishmania. We show that ribosomes move ...
ORGANISM(S): Leishmania infantum 
2021-07-23 | PXD020667 | Pride
Ribosome Leishmania infantum Ddx3 Label-free quantitative proteomics Cotranslational protein ubiquitination Orbitrap fusion 
UnknownSubjective feeling of control during fNIRS-based neurofeedback targeting the DL-PFC is related to neural activation determined with short-channel correction.
Not available
S-EPMC10431651 | biostudies-literature
UnknownBlinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC6027091 | biostudies-literature
UnknownEfficient enrichment of plasma-derived extracellular vesicles from small volumes of bovine blood.
Not available
S-EPMC12597144 | biostudies-literature
ProteomicsIdentifying altered mouse gephyrin interactome after sleep deprivation
GABAergic transmission controls cortical sleep, however the molecular determinants of GABAergic control of this phenomenon are unknown. We used immunoprecipitation of the inhibitory postsynaptic protein gephyrin to identify gephyrin interactors at ZT6 (sleep) and ZT6 with sleep deprivation (ZT6SD).
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD048929 | Pride
Mouse Gephyrin interactome Sleep deprivation 
UnknownUCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial.
Not available
S-EPMC11575699 | biostudies-literature
UnknownPooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy.
Not available
S-EPMC6075828 | biostudies-literature
UnknownGenome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.
Not available
S-EPMC11773457 | biostudies-literature
GenomicsMDS Sequencing Project Cancer Cell
Myelodysplastic syndromes (MDS) are uncommon entities, heterogeneous clinically and cytogenetically. The aim of the present study is to determine genetic alteration in this subset of patients. Expected results: Identification of new aberrations and genetic markers in order to detect novel genes invo...
EGAS00001001011 | EGA
UnknownUsing Artificial Intelligence to Find the Optimal Margin Width in Hepatectomy for Colorectal Cancer Liver Metastases.
Not available
S-EPMC9161118 | biostudies-literature
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