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TranscriptomicsFoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.
Activated phosphoinositide 3-kinase (PI3K)-AKT signaling appears to be an obligate event in the development of cancer. The highly related members of the mammalian FoxO transcription factor family, FoxO1, FoxO3, and FoxO4, represent one of several effector arms of PI3K-AKT signaling, prompting geneti...
ORGANISM(S): Mus musculus 
2011-03-16 | E-GEOD-27932 | biostudies-arrayexpress
TranscriptomicsHuman GBM tumor vs Normal Human DNA
We have developed a nonheuristic genome topography scan (GTS) algorithm to characterize the patterns of genomic alterations in human glioblastoma (GBM), identifying frequent p18INK4C and p16INK4A codeletion. Functional reconstitution of p18INK4C in GBM cells null for both p16INK4A and p18INK4C resul...
ORGANISM(S): Homo sapiens 
2008-04-29 | E-GEOD-9177 | biostudies-arrayexpress
TranscriptomicsFeedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development
We have developed a nonheuristic genome topography scan (GTS) algorithm to characterize the patterns of genomic alterations in human glioblastoma (GBM), identifying frequent p18INK4C and p16INK4A codeletion. Functional reconstitution of p18INK4C in GBM cells null for both p16INK4A and p18INK4C resul...
ORGANISM(S): Homo sapiens 
2008-04-29 | E-GEOD-9200 | biostudies-arrayexpress
UnknownSouvenaid in the management of mild cognitive impairment: an expert consensus opinion.
Not available
S-EPMC6698334 | biostudies-literature
UnknownSafety of dostarlimab in combination with chemotherapy in patients with primary advanced or recurrent endometrial cancer in a phase III, randomized, placebo-controlled trial (ENGOT-EN6-NSGO/GOG-3031/RUBY).
Not available
S-EPMC11439170 | biostudies-literature
UnknownDifferentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort.
Not available
S-EPMC11408082 | biostudies-literature
UnknownEpidemiology of pain, delirium, psychiatric disorders, discomfort and sedation-analgesia management in the intensive care unit: a one-day nationwide study.
Not available
S-EPMC12606798 | biostudies-literature
UnknownNetwork impact score is an independent predictor of post-stroke cognitive impairment: A multicenter cohort study in 2341 patients with acute ischemic stroke.
Not available
S-EPMC9079101 | biostudies-literature
UnknownInsights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.
Not available
S-EPMC12120264 | biostudies-literature
UnknownSex Differences in Frequency, Severity, and Distribution of Cerebral Microbleeds.
Not available
S-EPMC11581520 | biostudies-literature
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