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UnknownNetwork pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss.
Not available
S-EPMC9359200 | biostudies-literature
UnknownHistone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Not available
S-EPMC11105029 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
ProteomicsEIF3F regulates cell migration and metastasis in human lung adenocarcinoma
The basic understanding of the biological effects of eukaryotic translation initiation factors (EIFs) remains incomplete. Here, we analyzed the function of EIF3F, which is commonly found to be overexpressed in human lung adenocarcinoma, and discovered that EIF3F promotes cell migration and metastasi...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-25 | PXD010097 | Pride
Cancer Lung Human lung adenocarcinoma Label-free quantitative proteome analysis 
UnknownNew insights into the QuikChange™ process guide the use of Phusion DNA polymerase for site-directed mutagenesis.
Not available
S-EPMC4333370 | biostudies-literature
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
UnknownSTK11 is required for the normal program of ciliated cell differentiation in airways.
Not available
S-EPMC6796922 | biostudies-literature
UnknownPharmacophylogenetic insights into Scutellaria strigillosa Hemsl.: chloroplast genome and untargeted metabolomics, quantitative analysis and antibacterial analysis.
Not available
S-EPMC11461247 | biostudies-literature
TranscriptomicsBrd4 and JMJD6-associated Anti-pause Enhancers in Regulation of Transcriptional Pause Release
Distal enhancers characterized by H3K4me1 mark play critical roles in developmental and transcriptional programs. However, potential roles of specific distal regulatory elements in regulating RNA Polymerase II (Pol II) promoter-proximal pause release remain poorly investigated. Here we report that a...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-51633 | biostudies-arrayexpress
UnknownBiological Mechanisms of Aflatoxin B1-Induced Bile Metabolism Abnormalities in Ducklings.
Not available
S-EPMC11506432 | biostudies-literature
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