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TranscriptomicsTimecourse gene expression profiling of DLBCL cell line Karpas422 after EZH2 inhibitor treatment
Ezh2 protein is the enzymatic component of the Polycomb Repressive Complex (PRC)-2, which represses its target genes by methylating lysine 27 of histone H3 (H3K27) and regulates cell proliferation and differentiation during embryonic development. Recently, hot-spot mutations of Ezh2 have been identi...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-41315 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures for practical radiation biodosimetry
Genome-wide analysis of miRNA expression was performed in Activin A and Wnt3a-treated mouse ESCs during the different stages of DE differentiation to identify candidate miRNAs likely to be involved in Wnt3a and Activin A induced DE formation. Our analysis exhibited a distinct miRNA expression finger...
ORGANISM(S): Mus musculus 
2012-04-08 | E-GEOD-29093 | biostudies-arrayexpress
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