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Differentiation of mesenchymal stem cells relies on precise control of tightly controlled genetic programme where specific sets of genes are up-regulated. Identification of miRNAs that are modulated during this process should help to better understand cho
ORGANISM(S): Homo sapiens 
Regulatory T (Treg) cells actively control pathological immune responses and immunotherapeutic strategies triggering an increase in the number and/or the function of endogenous Treg cells emerge as a promising therapeutic strategy in autoimmune diseases to restore tolerance. A remarkable heterogenei...
ORGANISM(S): Mus musculus 
Background: Many tools used to analyze microarrays in different conditions have been described. However, the integration of the deregulated genes within coherent metabolic pathways is lacking. Currently no objective selection criterion, based on biological functions exists, to determine a threshold ...
ORGANISM(S): Homo sapiens 
Type I interferon (IFN) is a family of 15 cytokines (in human 13α, 1β,1ω) which exert several cellular functions through the binding to a common receptor. Despite the initial activation of the same Jak/Stat signalling pathway, the cellular response may be different depending on the type I IFN subtyp...
ORGANISM(S): Homo sapiens 
In the present study, we were interested in gene expression changes in the pectoralis muscle of juvenile king penguins during the transition from terrestrial to marine life. Strictly terrestrial during their first year after hatching, king penguin chicks must then depart to sea to reach nutritional ...
ORGANISM(S): Aptenodytes patagonicus 
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