Sort   by:  
 Page size 
GenomicscIAP1/2 antagonism induces antigen-specific T cell dependent immunity
cIAP1/2 antagonism induces antigen-specific T cell dependent immunity
PRJNA917692 | ENA
TranscriptomicscIAP1/2 antagonism induces antigen-specific T cell dependent immunity
Checkpoint blockade immunotherapy has failed in pancreatic cancer and other poorly responsive tumor types in part due to inadequate T cell priming. Naïve T cells can receive co-stimulation not only via CD28 but also through TNF superfamily receptors that signal via NF-κB. Antagonists of the ubiquiti...
ORGANISM(S): Mus musculus 
2023-01-25 | GSE222095 | GEO
UnknownE2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding.
Not available
S-EPMC6201919 | biostudies-literature
UnknownCytoplasmic and Nuclear Functions of cIAP1.
Not available
S-EPMC8869227 | biostudies-literature
UnknownBoth cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
Not available
S-EPMC2575330 | biostudies-literature
UnknowncIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity.
Not available
S-EPMC10036868 | biostudies-literature
UnknownTumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
Not available
S-EPMC2878517 | biostudies-literature
UnknownTRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein.
Not available
S-EPMC9724401 | biostudies-literature
UnknownInhibition of cIAP1 as a strategy for targeting c-MYC-driven oncogenic activity.
Not available
S-EPMC6176641 | biostudies-literature
UnknownA novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation.
Not available
S-EPMC5575267 | biostudies-literature
Sort   by:  
 Page size