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Abstract:

Background: Quercetin is a flavonoid with various probiotic properties, demonstrating anti-inflammatory, anti-oxidative, anti-cancer, and anti-obesity effects in humans and animals. However, quercetin’s effect on enterotoxigenic Escherichia coli (ETEC) K88-induced host body injury...

2026-01-14 | MTBLS13677 | MetaboLights
Pancreatic adenocarcinoma has the worst mortality of any solid cancer. To evaluate the clinical implications of genomic alterations in this tumor type, we performed whole-exome analyses of 24 tumors, targeted genomic analyses of 77 tumors, and used non-invasive approaches to examine tumor-specific ...
Nanoparticle elasticity plays crucial roles in determining nanoparticles’ physiological performances. However, the underlying mechanisms by which nanoparticle elasticity does so remain unknown.Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity ...
ORGANISM(S): Mus Musculus 
2022-05-20 | PXD034004 |
Clinical Implications of Genomic Alterations in the Tumour and Circulation of Pancreatic Cancer Patients
Small extracellular vesicles (sEVs) are important mediators of intercellular communication with respect to diverse pathophysiological processes. The heterogeneity of sEV populations is a key factor in pursuing the sEV-related translational and basic research into forward but remains challenging for ...
ORGANISM(S): Mus Musculus (mouse) 
Circulating tumor cells exit circulation while maintaining multicellularity augmenting metastatic potential
Background: Mice lacking either T-cell intracellular antigen 1 (TIA1) or TIA1-related/like protein (TIAR/TIAL1) show high rates of embryonic lethality, suggesting a relevant role for these proteins during embryonic development. However, intrinsic molecular and cellular consequences of either TIA1 or...
ORGANISM(S): Mus musculus 
Obstetric complications in pregnant people with Fontan Circulation: identifying candidate pathologic pathways in the placenta
RNA-seq to assess the impact of circulation on hematopoietic stem cell differentiation.
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