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TranscriptomicsTranscription profiling of human HT29 cells sensitive and resistant to 10e-5M methotrexate
The abstract of the associated publication (Selga E, Noé V, Ciudad CJ. Biochemical Pharmacology 2007 Sep 8; Article in press) is the following:; While studying differentially expressed genes between sensitive and 10-5 M Methotrexate (MTX) resistant HT29 human colon cancer cells, we identified some ...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9412 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human HT29 colon cancer cells to investigate the role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexate
A summary of the work associated to these microarrays is the following:; Methotrexate (MTX) is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11440 | biostudies-arrayexpress
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