Sort   by:  
 Page size 
GenomicsMus Musculus strain:CK-p25
Transcriptome Changes of CK-p25 Mice
PRJNA235922 | ENA
GenomicsH3K9ac data from mouse models suggest structural changes in the murine brain epigenome that involve the nuclear lamina
To explore whether tau-related epigenomic changes that we found human brain H3K9ac data (Synapse ID: syn4896408) are recapitulated in mouse models known to accumulate tau, we generated hippocampal H3K9ac ChIP-seq profiles from two different mouse models each at an early and a late stage of neurodege...
ORGANISM(S): Mus musculus 
2018-12-07 | GSE97560 | GEO
TranscriptomicsGamma entrainment binds higher order brain regions and alleviates neurodegeneration
We report the RNA-Seq data of microglia from CK-p25 mice visual cortex
ORGANISM(S): Mus musculus 
2019-03-29 | GSE115244 | GEO
GenomicsConserved epigenomic signatures between mouse and human elucidate immune basis of Alzheimer's disease
Alzheimer’s disease (AD) is a severe1 age-related neurodegenerative disorder characterized by accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles, synaptic and neuronal loss, and cognitive decline. Several genes have been implicated in AD, but chromatin state alterations during ne...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-65159 | biostudies-arrayexpress
GenomicsMicroglia-specific loss of PU.1 function rescues neurodegenerative phenotypes in a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by progressive decline of cognitive ability. An important component of AD, and other chronic neurodegenerative diseases, is generation of an innate inflammatory response within the CNS, characterized by activation of...
ORGANISM(S): Mus musculus 
2021-01-01 | GSE117868 | GEO
TranscriptomicsNeurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
DNA double strand breaks (DSBs) are linked to neurodegeneration and senescence. However, it is not clear how DSB-bearing neurons influence neuroinflammation associated with neurodegeneration. Here, we characterize DSB-bearing neurons from the CK-p25 mouse model of neurodegeneration using single-nucl...
ORGANISM(S): Mus musculus 
2022-05-10 | GSE174265 | GEO
GenomicsGamma entrainment binds higher order brain regions and alleviates neurodegeneration
Gamma entrainment binds higher order brain regions and alleviates neurodegeneration
PRJNA474231 | ENA
GenomicsNeurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
Neurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
PRJNA729044 | ENA
UnknownGamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.
Not available
S-EPMC6697125 | biostudies-literature
UnknownVibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function.
Not available
S-EPMC10233036 | biostudies-literature
Sort   by:  
 Page size