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TranscriptomicsExpression Profiles of HepG2 cells treated with following compounds: Azathriopine, Furan, Tetradecanoyl phorbol acetate, Tetrachloroethylene, Diazinon and Dmannitol
The transcriptomic changes induced in the human liver cell line HepG2 by Azathriopine (250M-BM-5M, Sigma-Aldrich), Furan (2mM, Sigma-Aldrich), Tetradecanoyl phorbol acetate (500nM, Sigma-Aldrich), Tetrachloroethylene (2mM, Sigma-Aldrich), Diazinon (250M-BM-5M, Sigma-Aldrich) and Dmannitol (250M-BM...
ORGANISM(S): Homo sapiens 
2015-01-13 | E-GEOD-58235 | biostudies-arrayexpress
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
no omics definedTranscription profiling of mouse embryonic stem cell line D3 differentiation cultures treated by different concentrations of flusilazole.
This study investigated the effect of the compound concentration of Flusilazole on gene expression responses in Embryonic Stem Cell Differentiation Cultures. Flusilazole is used in agriculture as a fungicide, but has developmental toxic effects. To study the effects of its concentration on developme...
ORGANISM(S): Mus Musculus 
2011-07-02 | E-TABM-1027 | biostudies-arrayexpress
TranscriptomicsLow dose human APAP exposure
Acetaminophen is the primary cause of acute liver toxicity in Europe/USA. Therefore, the FDA reconsiders recommendations concerning safe acetaminophen dosage/use. Current tests for liver toxicity are no ideal predictive markers for liver injury. Here, ‘omics techniques (global analysis of metabolomi...
ORGANISM(S): Homo sapiens 
2011-07-07 | E-GEOD-30418 | biostudies-arrayexpress
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