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TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
TranscriptomicsHuman and marmoset trophoblast stem cells differ in signalling requirements and recapitulate divergent modes of trophoblast invasion
We derive experimental conditions for the derivation of marmoset trophoblast like cells. Marmoset naïve PSC form extraembryonic mesoderm in human TSC conditions, whilst TGFβ/NODAL, FGF/ERK and WNT signalling control marmoset peri- and postimplantation trophoblast identity.
ORGANISM(S): Callithrix jacchus 
2024-11-21 | E-MTAB-12463 | biostudies-arrayexpress
TranscriptomicsComparative transcriptome analysis of the CO2 sensing pathway via differential expressions of carbonic anhydrase in Cryptococcus neoformans
Carbon dioxide (CO2) sensing, transport, and metabolism play a pivotal role in survival and proliferation of pathogenic microbes infecting human host from natural environments due to the drastic difference of CO2 levels. Carbonic anhydrases (CAs) are not only key CO2-metabolic enzymes catalyzing rev...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-31 | E-GEOD-21192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse SCN after 30-min light pulse
The transmission of information about the photic environment to the circadian clock involves a complex array of neurotransmitters, receptors, and second messenger systems. Using laser capture microscopy and microarray analysis, a population of genes rapidly induced by light in the suprachiasmatic n...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6904 | biostudies-arrayexpress
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