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TranscriptomicsExpression data from pooled biological replicates (n=6) from MEF2D knockdown in neonatal rat ventricular myocytes (NRVMs)
Differentiation and maintenance of cardiac muscle is a complex biological process. MEF2D appears to play an important role in the regulation of cardiomyocyte homeostasis. We knocked down expression of MEF2D in NRVMs, and assessed global expression pattern changes in MEF2D knockdown against a negativ...
ORGANISM(S): Rattus norvegicus 
2015-08-31 | E-GEOD-72157 | biostudies-arrayexpress
TranscriptomicsDeciphering regulatory mechanisms associated with hemicellulose degradation in Neurospora crassa
Hemicellulose, the second most abundant plant biomass fraction after cellulose, is widely viewed as a potential feedstock for the production of liquid fuels and other value-added materials. Degradation of hemicellulose by filamentous fungi requires production of many different enzymes, which are ind...
ORGANISM(S): Neurospora crassa 
2012-03-26 | E-GEOD-34098 | biostudies-arrayexpress
TranscriptomicsHistone H3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells
Lysine 56 acetylation in the helical core of histone H3 opens yeast chromatin and enables histone gene transcription, DNA replication, DNA repair, and prevents epigenetic silencing. While K56Ac is globally abundant in yeast and flies its presence has been uncertain in mammals. We show here using mas...
ORGANISM(S): Homo sapiens 
2009-02-09 | E-GEOD-14749 | biostudies-arrayexpress
ProteomicsEgg proteome changes during fertilization in sterlet Acipenser ruthenus
Sturgeons, producers of black caviar, are one of the most valuable wildlife commodities on earth (Pikitch et al., 2005). They appeared approximately 200 million years ago, and are known as living fossils (Bemis et al., 1997). Sturgeon populations dramatically declined as a result of overfishing, poa...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2017-06-12 | PXD006232 | Pride
Protein Fertilzation Egg Quantification 
TranscriptomicsTBP ChIP-chip on Jurkat cells
During mitosis, TATA-binding protein(TBP), which remains bound to DNA during mitosis, recruits PP2A and also interacts with a subunit of the condensin complex to allow efficient dephosphorylation and inactivation of condensin near these promoters to inhibit their compaction. These result suggest tha...
ORGANISM(S): Homo sapiens 
2010-04-03 | E-GEOD-12256 | biostudies-arrayexpress
UnknownVarenicline as a treatment for cannabis use disorder: A placebo-controlled pilot trial.
Not available
S-EPMC8665036 | biostudies-literature
UnknownEffects of baseline CSF α-synuclein on regional brain atrophy rates in healthy elders, mild cognitive impairment and Alzheimer's disease.
Not available
S-EPMC3877372 | biostudies-literature
UnknownEngineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.
Not available
S-EPMC1236553 | biostudies-literature
TranscriptomicseQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors
Motivation: Identification of eQTL, the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. Methods: We have developed a method for Hidden Ex...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-40364 | biostudies-arrayexpress
ProteomicsEvaluation of a bead-free immunoprecipitation technique coupled with tandem mass spectrometry for identification of plant-virus protein interactions (DeBlasio_JBT_2017)
Potato leafroll virus (PLRV) is an aphid-borne, RNA virus in the Luteoviridae that causes significant loss to potato production worldwide. Precision methods to block virus infection in plants or the transmission of a virus by the insect represent new approaches to virus disease management and requir...
ORGANISM(S): Nicotiana benthamiana 
2018-10-24 | PXD006338 | Pride
Host-pathogen interactions Bead-free immunoprecipitation  plant-virus interactome  tandem mass spectrometry Luteoviridae Polerovirus Molecular virology Potato leafroll virus Phloem-limited 
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