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TranscriptomicsIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse (RNA-Seq)
Methylation of cytosines (5meC) is a widespread heritable DNA modification. During mammalian development, two global demethylation events are followed by waves of de novo DNA methylation. In vivo mechanisms of DNA methylation establishment are largely uncharacterized. Here we use Saccharomyces cerev...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-02 | E-GEOD-66908 | biostudies-arrayexpress
GenomicsIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse (Bisulfite-Seq)
Methylation of cytosines (5meC) is a widespread heritable DNA modification. During mammalian development, two global demethylation events are followed by waves of de novo DNA methylation. In vivo mechanisms of DNA methylation establishment are largely uncharacterized. Here we use Saccharomyces cerev...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-02 | E-GEOD-66905 | biostudies-arrayexpress
GenomicsIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse (ChIP-Seq yeast)
Methylation of cytosines (5meC) is a widespread heritable DNA modification. During mammalian development, two global demethylation events are followed by waves of de novo DNA methylation. In vivo mechanisms of DNA methylation establishment are largely uncharacterized. Here we use Saccharomyces cerev...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-02 | E-GEOD-66909 | biostudies-arrayexpress
GenomicsIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse (Mnase-Seq)
Methylation of cytosines (5meC) is a widespread heritable DNA modification. During mammalian development, two global demethylation events are followed by waves of de novo DNA methylation. In vivo mechanisms of DNA methylation establishment are largely uncharacterized. Here we use Saccharomyces cerev...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-02 | E-GEOD-66907 | biostudies-arrayexpress
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
UnknownSafety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Not available
S-EPMC7723445 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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