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TranscriptomicsGene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFb
Cancer cells exhibit the ability to proliferate indefinitely, but paradoxically, overexpression of cellular oncogenes in primary cells can result in a rapid and irreversible cell cycle arrest known as oncogene-induced senescence (OIS). However, we have shown that constitutive overexpression of the o...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-GEOD-31002 | biostudies-arrayexpress
UnknownRemote C-H insertion of vinyl cations leading to cyclopentenones.
Not available
S-EPMC5643953 | biostudies-literature
UnknownCrystal structure of poly[N,N-diethyl-2-hy-droxy-ethan-1-aminium [μ3-cyanido-κ(3) C:C:N-di-μ-cyanido-κ(4) C:N-dicuprate(I)]].
Not available
S-EPMC4992900 | biostudies-literature
UnknownRole of c-Abl tyrosine kinase in smooth muscle cell migration.
Not available
S-EPMC3989717 | biostudies-literature
TranscriptomicsEffects of upf1delta on RNA stability
The Upf1 protein is a major factor in nonsense-mediated decay. We used an in vivo labelling system (Cleary et al. 2005 Nat Biotechnol. 23, 232-7) to estimate the decay rates of upf1delta and wild type cells over-expressing the transcription factor Mei4.
ORGANISM(S): Schizosaccharomyces pombe 
2013-06-03 | E-MTAB-1324 | biostudies-arrayexpress
TranscriptomicsExpression profiling of MLL-AF10 myeloid leukemia cellular subsets
Leukemia cells from mice with MLL-AF10 AML were fractionated into separate sub-populations on the basis of c-kit expression, which correlates with MLL LSC frequency (Somervaille and Cleary, 2006). The sorted AML sub-populations exhibited substantial differences in their frequencies of AML CFCs/LSCs ...
ORGANISM(S): Mus musculus 
2009-02-06 | GSE13692 | GEO
UnknownGene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ.
Not available
S-EPMC3180192 | biostudies-literature
TranscriptomicsTranscription profiling of human MLL-AF10 myeloid leukemia cellular subsets
Leukemia cells from mice with MLL-AF10 AML were fractionated into separate sub-populations on the basis of c-kit expression, which correlates with MLL LSC frequency (Somervaille and Cleary, 2006). The sorted AML sub-populations exhibited substantial differences in their frequencies of AML CFCs/LSCs...
ORGANISM(S): Mus musculus 
2009-02-21 | E-GEOD-13692 | biostudies-arrayexpress
UnknownReactivity Profiles of Diazo Amides, Esters, and Ketones in Transition-Metal-Free C-H Insertion Reactions.
Not available
S-EPMC7059911 | biostudies-literature
TranscriptomicsEffects of deletion of RNA-binding proteins on RNA stability using an in vivo labelling system to estimate the decay rates of RBP mutants and wild type S. pombe cells
To investigate the contribution of RNA-binding proteins to the regulation of RNA decay we used an in vivo labelling system (Cleary et al. 2005 Nat Biotechnol. 23, 232-7) to estimate the decay rates of RBP mutants and wild type S. pombe cells
ORGANISM(S): Schizosaccharomyces pombe 
2014-11-06 | E-MTAB-2318 | biostudies-arrayexpress
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