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TranscriptomicsTranscription profiling by array of Arabidopsis mutant for rhd2/ArtbohC
Aim: To determine the effect of an AtrbohC mutation on the gene expression pattern in primary root tissue, to identify candidate genes acting downstream of AtrbohC, particularly any encoding antioxidant-related proteins, signal transduction components or proteins known to be required for normal roo...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6165 | biostudies-arrayexpress
UnknownThe integration of mixed methods data to develop the quality of life - aged care consumers (QOL-ACC) instrument.
Not available
S-EPMC8672336 | biostudies-literature
UnknownOutpatient treatment of decompensated heart failure: A systematic review and study level meta-analysis.
Not available
S-EPMC11911626 | biostudies-literature
ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (validation)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44437 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis sfr6 freezing-sensitive mutant and cls8 chilling sensitive mutant to investigate the molecular basis of chilling and freezing stress
Our analysis of the sfr6 freezing-sensitive mutant (Knight, H., Veale, E., Warren, G. J. and Knight, M. R. (1999). Plant Cell 11, 875-886.) and cls8 (unpublished) chilling-sensitive mutant of Arabidopsis, has revealed that the expression of certain cold-regulated genes is aberrant in both these mut...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6167 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)
Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males). The volunteers fasted overnight for 10 hours prior to collection of blood samples (but they were allowed water). 5 blood samples were collected from eac...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-TABM-7 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cultured human cells response to stress (heat shock)
TT3 and TN are cell cycle time courses and should be centered or transformed before clustering or computing fourier scores. The preferred method is SVD centering preceded by KNNImpute missing-value estimation, although mean-centering is a viable alternative. Hela Heat 42 degrees time course has...
ORGANISM(S): Homo sapiens 
2006-06-06 | E-SMDB-1577 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) mutants reveals Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and programmed cell death
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-05 | E-MEXP-1136 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis auxin resistant axr4 mutant and wild-type Col0
The plant hormone auxin represents an important regulator of growth and development. Significant insight into the mechanisms of auxin action have been obtained from studies of auxin resistant mutants such as aux1 and axr3. The Arabidopsis axr4 mutant was identified in a screen for auxin resistant ro...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6168 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis AtrbohB null mutant in response to heat to examine the molecular basis of respiratory burst-mediated thermotolerance in Arabidopsis
We have been determining signalling components essential for heat tolerance in Arabidopsis thaliana (Larkindale, J., and Knight, M.R. (2002). Protection against heat stress-induced oxidative damage in Arabidopsis involves calcium, abscisic acid, ethylene, and salicylic acid. Plant Physiol 128, 682-6...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6154 | biostudies-arrayexpress
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