Sort   by:  
 Page size 
UnknownGenome-wide identification of susceptibility alleles for viral infections through a population genetics approach.
Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants. Virus diversity (the number of different viruses in a geographic region) was used to...
S-EPMC2824813 | biostudies-literature
UnknownBalancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving.

Background

Several susceptibility genetic variants for autoimmune diseases have been identified. A subset of these polymorphisms displays an opposite risk profile in different autoimmune conditions. This observation open interesting questions on the evolutionary forces shaping the frequency ...
S-EPMC3141431 | biostudies-literature
UnknownThe landscape of human genes involved in the immune response to parasitic worms.

Background

More than 2 billion individuals worldwide suffer from helminth infections. The highest parasite burdens occur in children and helminth infection during pregnancy is a risk factor for preterm delivery and reduced birth weight. Therefore, helminth infections can be regarded as a str...
S-EPMC2940816 | biostudies-literature
UnknownGuidelines for the use of flow cytometry and cell sorting in immunological studies.
Not available
S-EPMC9165548 | biostudies-literature
Sort   by:  
 Page size