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MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Simulated)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS235 | MetaboLights
MetabolomicsA Clinical Urine Metabolomics Dataset for Urological Malignancies
Renal cell carcinoma, bladder cancer, and prostate cancer rank among the most common urological malignancies, yet clinically satisfactory non-invasive screening tools for these cancers are still lacking. Here we present an untargeted urine metabolomics dataset generated by liquid chromatography coup...
2026-06-27 | MTBLS14865 | MetaboLights
MetabolomicsMetabolomics study of COVID-19 patients in four different clinical stages

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To understand the pathobiology of SARS-CoV-2 in humans it is necessary to unravel the metabolic changes that are produced in the individuals...

2025-01-24 | MTBLS3800 | MetaboLights
MetabolomicsMetabolomic signatures discriminate horses with clinical signs of atypical myopathy from healthy co-grazing horses
Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objective of this study was to compare the blood metabolomic profiles of horses...
2021-08-31 | MTBLS2579 | MetaboLights
MetabolomicsCHOICE clinical weight loss study
Not available
ORGANISM(S): Homo sapiens;Rattus norvegicus 
ST000661 | MetabolomicsWorkbench
MetabolomicsExpanding the clinical use of DBS: through a metabolomic and a lipidomic evaluation

Personalized medicine aims to tailor healthcare to individual characteristics, relying on precise biological data and patient monitoring. Metabolomics and lipidomics play a key role in this approach, providing real-time insights into metabolic states and enabling accurate diagnosis and treatment ...

2026-02-25 | MTBLS13382 | MetaboLights
MetabolomicsCirculatory metabolomics reveals the association of the metabolites with clinical features in the patients with intrahepatic cholestasis of pregnancy

OBJECTIVE: Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse pregnancy outcomes to the mother and fetus. As yet, the metabolic profiles and the association of the clinical features remain obscure.

METHODS: Fifty sev...

2022-03-01 | MTBLS2627 | MetaboLights
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
MetabolomicsLinking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in pediatric hematopoietic stem cell transplantation

BACKGROUND: Hematopoietic stem cell transplantation is a curative procedure for a variety of conditions. Despite major advances, a plethora of adverse clinical outcomes can develop post-transplantation including graft-versus-host disease and infections, which remain the major cau...

2022-05-11 | MTBLS4065 | MetaboLights
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