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In an effort to define the biological determinants of stage I chemo-sensitivity, we undertook a genome-wide miRNA expression profile in a cohort of 89 stage I patients (24 of which relapsed) with a complete follow up of twelve years, selected from a single tumor tissue collection of more than 1300 s...
ORGANISM(S): Homo sapiens 
In order to study the effects of trabectedin in chronic myelomonocytic leukemia and in juvenile myelomonocytic leukemia, we performed whole genome transcriptional profiling of a model cell line treated under either the reference drug for CMML / JMML (Azacitidine) or trabectedin.
ORGANISM(S): Homo sapiens 
In order to determine the difference at the microRNA level of different ovarian tumor histotypes, we have performed a whole miRNA screening on 183 patients of grade 1 ovarian cancer. Additionally, we compared the miRNA profile of tumors with standard ovarian epithelial cells (HOSE).
ORGANISM(S): Homo sapiens 
Gene expression profiles of 402-91 FUS-CHOP type I cells have been compared to 402-91/ET cells made resistant to Trabectedin Experiments were performed on purified RNA from independent batches of 402-91 and 402-91/ET cells without drug treatment.
ORGANISM(S): Homo sapiens 
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